Proteintech

TIMM17B Polyclonal Antibody

TIMM17B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

TIMM17B Antibody (11062-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon cancer using 11062-1-AP (TIMM17B antibody) at dilution of 1:50 (under 10x lens).

TIMM17B Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11062-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TIMM17B Fusion Protein Ag1504 (1-172 aa encoded by BC010142)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEEYAREPC PWRIVDDCGG AFTMGVIGGG VFQAIKGFRN APVGIRHRLR GSANAVRIRA PQIGGSFAVW GGLFSTIDCG LVRLRGKEDP WNSITSGALT GAVLAARSGP LAMVGSAMMG GILLALIEGV GILLTRYTAQ QFRNAPPFLE DPSQLPPKDG TPAPGYPSYQ QYH (1-172 aa encoded by BC010142)

Target Information

This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria.

Cell reports

Akabane S,Watanabe K,Kosako H,Yamashita SI,Nishino K,Kato M,Sekine S,Kanki T,Matsuda N,Endo T,Oka T

Tue May 30 00:00:00 UTC 2023

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

The Journal of cell biology

Richter F,Dennerlein S,Nikolov M,Jans DC,Naumenko N,Aich A,MacVicar T,Linden A,Jakobs S,Urlaub H,Langer T,Rehling P

Mon Feb 04 00:00:00 UTC 2019

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

The Journal of cell biology

Richter F,Dennerlein S,Nikolov M,Jans DC,Naumenko N,Aich A,MacVicar T,Linden A,Jakobs S,Urlaub H,Langer T,Rehling P

Mon Feb 04 00:00:00 UTC 2019

Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8⁺ T Cells.

Cell metabolism

Hu Z,Qu G,Yu X,Jiang H,Teng XL,Ding L,Hu Q,Guo X,Zhou Y,Wang F,Li HB,Chen L,Jiang J,Su B,Liu J,Zou Q

Tue Aug 06 00:00:00 UTC 2019

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Molecular cell

Kang Y,Stroud DA,Baker MJ,De Souza DP,Frazier AE,Liem M,Tull D,Mathivanan S,McConville MJ,Thorburn DR,Ryan MT,Stojanovski D

Thu Aug 03 00:00:00 UTC 2017

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Molecular cell

Kang Y,Stroud DA,Baker MJ,De Souza DP,Frazier AE,Liem M,Tull D,Mathivanan S,McConville MJ,Thorburn DR,Ryan MT,Stojanovski D

Thu Aug 03 00:00:00 UTC 2017

Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.

Molecular cell

Vukotic M,Nolte H,König T,Saita S,Ananjew M,Krüger M,Tatsuta T,Langer T

Thu Aug 03 00:00:00 UTC 2017

Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.

Molecular cell

Vukotic M,Nolte H,König T,Saita S,Ananjew M,Krüger M,Tatsuta T,Langer T

Thu Aug 03 00:00:00 UTC 2017

Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma.

American journal of physiology. Endocrinology and metabolism

Ogunbileje JO,Porter C,Herndon DN,Chao T,Abdelrahman DR,Papadimitriou A,Chondronikola M,Zimmers TA,Reidy PT,Rasmussen BB,Sidossis LS

Mon Aug 01 00:00:00 UTC 2016

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly.

Scientific reports

Wrobel L,Sokol AM,Chojnacka M,Chacinska A

Mon Jun 06 00:00:00 UTC 2016

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly.

Scientific reports

Wrobel L,Sokol AM,Chojnacka M,Chacinska A

Mon Jun 06 00:00:00 UTC 2016

The type III system-secreted effector EspZ localizes to host mitochondria and interacts with the translocase of inner mitochondrial membrane 17b.

Infection and immunity

Shames SR,Croxen MA,Deng W,Finlay BB

Thu Dec 01 00:00:00 UTC 2011

The type III system-secreted effector EspZ localizes to host mitochondria and interacts with the translocase of inner mitochondrial membrane 17b.

Infection and immunity

Shames SR,Croxen MA,Deng W,Finlay BB

Thu Dec 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: inner mitochondrial membrane preprotein translocase; Mitochondrial import inner membrane translocase subunit Tim17-B; translocator of inner mitochondrial membrane 17 kDa, b; translocator of inner mitochondrial membrane 17b; translocator of inner mitochondrial membrane b

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Gene Aliases: 17kDa; DXS9822; JM3; mTim17b; RGD1561744; Sfc3; TIM17B; TIMM17B

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UniProt ID: (Human) O60830, (Mouse) Q9Z0V7

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Entrez Gene ID: (Human) 10245, (Mouse) 21855, (Rat) 317374

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Function(s)

protein channel activity P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Process(es)

transport intracellular protein transport protein transport protein transmembrane transport protein targeting to mitochondrion protein import into mitochondrial matrix

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TIMM17B Polyclonal Antibody

TIMM17B Antibody (11062-1-AP) in IHC (P)

Product Details

11062-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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