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Invitrogen
TIMM44 Polyclonal Antibody
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FIGURE: 1 / 4
TIMM44 Antibody (PA5-106383) in ICC/IF
Immunofluorescent analysis of TIMM44 in HUVEC cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and TIMM44 polyclonal antibody (Product # PA5-106383) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-106383
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TIMM44(Accession O43615), corresponding to amino acid residues M1-S48.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2817651
Product Specific Information
Antibody detects endogenous levels of total TIMM44.
Target Information
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial import inner membrane translocase subunit TIM44; translocase of inner mitochondrial membrane 44 homolog; translocator of inner mitochondrial membrane 44; translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed
Gene Aliases: 0710005E20Rik; D8Ertd118e; MIMT44; TIM44; TIMM44
UniProt ID: (Human) O43615, (Mouse) O35857, (Rat) O35094
Entrez Gene ID: (Human) 10469, (Mouse) 21856, (Rat) 29635
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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