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Invitrogen
TIMM50 Recombinant Rabbit Monoclonal Antibody (0W6J4)
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Product Details
MA5-37851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
0W6J4
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TIMM50 (Q3ZCQ8)
Conjugate
Form
Liquid
Concentration
0.58 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897771
Product Specific Information
Positive Samples: 293T, HepG2, Mouse liver, Mouse brain
Immunogen sequence: MAASAAVFSR LRSGLRLGSR GLCTRLATPP RRAPDQAAEI GSRGSTKAQG PQQQPGSEGP SYAKKVALWL AGLLGAGGTV SVVYIFGNNP VDENGAKIPD
Target Information
TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homolog of yeast Tim50; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; similar to translocase of inner mitochondrial membrane 50 homolog; Tim50-like protein; translocase of inner mitochondrial membrane 50 homolog
Gene Aliases: 2810403L02Rik; AU015082; PRO1512; TIM50; TIM50L; TIMM50
UniProt ID: (Human) Q3ZCQ8, (Mouse) Q9D880
Entrez Gene ID: (Rat) 687295, (Human) 92609, (Mouse) 66525
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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