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Invitrogen
TIMM50 Recombinant Rabbit Monoclonal Antibody (JE51-61)
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TIMM50 Antibody (MA5-34881) in IHC (P)
Immunohistochemistry analysis of TIMM50 (Tim50) in paraffin-embedded human breast carcinoma tissue. Samples were heat mediated antigen retrieval with sodium citrate buffer (pH 6.0, 20 min) and blocked in 5% BSA (30 min, room temperature), incubated with TIMM50 (Tim50) monoclonal antibody (Product # MA5-34881) at a dilution of 1:50 (30 min, room temperature), and followed by HRP conjugated compact polymer sy... View More
Product Details
MA5-34881
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE51-61
Immunogen
Recombinant protein within Human TIM50 aa 1-109
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848789
Product Specific Information
Positive Control: A549, K562, MCF-7, human liver carcinoma tissue, human colon carcinoma tissue, human breast carcinoma tissue.
Target Information
TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homolog of yeast Tim50; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; Tim50-like protein; translocase of inner mitochondrial membrane 50 homolog
Gene Aliases: PRO1512; TIM50; TIM50L; TIMM50
UniProt ID: (Human) Q3ZCQ8
Entrez Gene ID: (Human) 92609
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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