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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TIMP1 Antibodies

          Invitrogen

          TIMP1 Monoclonal Antibody (102D1)

          Advanced Verification
          4 Published Figures
          36 References
          View all (52) TIMP1 antibodies

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          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite TIMP1 Monoclonal Antibody (102D1)

          • Antibody Testing Data (4)
          • Published Figures (4)
          • Advanced Verification (1)
          TIMP1 Antibody in Immunocytochemistry (ICC/IF)
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          TIMP1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          TIMP1 Antibody (MS608PABX) in ICC/IF

          Immunofluorescent analysis of TIMP-1 was performed using 70% confluent log phase MDA-MB-231 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with TIMP-1 (102D1) Mouse Monoclonal Antibody (Product # MS608PABX) at 1:250 dilution in0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          TIMP1 Antibody in Immunocytochemistry (ICC/IF)
          TIMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIMP1 Antibody in Western Blot (WB)
          TIMP1 Antibody in Western Blot (WB)
          TIMP1 Antibody in Immunohistochemistry (IHC)
          TIMP1 Antibody in Immunohistochemistry (IHC)
          TIMP1 Antibody in Western Blot (WB)
          TIMP1 Antibody in Western Blot (WB)
          TIMP1 Antibody

          Product Details

          MS608PABX

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          View 8 publications 8 publications

          Immunohistochemistry (IHC)

          -
          View 26 publications 26 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:250
          -

          Neutralization (Neu)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human, Mouse

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          102D1

          Immunogen

          Recombinant human TIMP-1.

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • Biotin 
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C

          RRID

          AB_417075

          Product Specific Information

          MS608PABX targets TIMP-1 in immunohistochemistry and western blot applications and shows reactivity with human samples.



          The MS608PABX immunogen is recombinant human TIMP-1.



          MS608PABX detects TIMP-1 which has a predicted molecular weight of approximately 21 kDa.

          Target Information

          TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Collagenase inhibitor; EPA; erythroid potentiating activity; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; Metalloproteinase inhibitor; Metalloproteinase inhibitor 1; MMP inhibitor; RP1-230G1.3; TIMP 1; TIMP-1; Tissue inhibitor of metalloproteinases 1

          View more View less

          Gene Aliases: CLGI; EPA; EPO; HCI; TIMP; TIMP-1; TIMP1

          View more View less

          UniProt ID: (Human) P01033

          View more View less

          Entrez Gene ID: (Human) 7076

          View more View less

          Function(s)
          protease binding cytokine activity protein binding growth factor activity metalloendopeptidase inhibitor activity metal ion binding
          Process(es)
          cell activation platelet degranulation aging positive regulation of cell proliferation response to hormone negative regulation of endopeptidase activity extracellular matrix disassembly response to cytokine wound healing negative regulation of apoptotic process negative regulation of catalytic activity response to peptide hormone negative regulation of membrane protein ectodomain proteolysis cartilage development negative regulation of trophoblast cell migration regulation of integrin-mediated signaling pathway
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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