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Immunogen sequence: SFSHPTSCSS SSEIMSVLFF YIMRYKQSDP ENPDNDRFVL AKRLSFVDVA TGWLGQGLGV ACGMAYTGKY FDRASYRVFC LMSDGESS
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 73%.
Strong TKTL1 protein expression has been correlated with a certain type of glucose metabolism (aerobic glycolysis; Warburg effect) and to cells which are affected by chronic complications of diabetic patients. In colon and urothelial carcinomas, expression at the protein level is correlated with invasiveness of tumors and poor patient survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: TK 2; Transketolase 2; transketolase-2; transketolase-like 1; Transketolase-like protein 1; Transketolase-related protein
Gene Aliases: TKR; TKT2; TKTL1
UniProt ID: (Human) P51854
Entrez Gene ID: (Human) 8277
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