Product References
TLE3 and TLE4-coordinated colonic macrophage-CD4+ T cell crosstalk maintains intestinal immune homeostasis.
Mucosal immunology
Li X,Zhang B,Zhang X,Yu S,Xue HH,Hu X
Wed Feb 01 00:00:00 UTC 2023
TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis.
Cancer research
Anstine LJ,Majmudar PR,Aponte A,Singh S,Zhao R,Weber-Bonk KL,Abdul-Karim FW,Valentine M,Seachrist DD,Grennel-Nickelson KE,Cuellar-Vite L,Sizemore GM,Sizemore ST,Webb BM,Thompson CL,Keri RA
Tue Apr 04 00:00:00 UTC 2023
TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis.
Cancer research
Anstine LJ,Majmudar PR,Aponte A,Singh S,Zhao R,Weber-Bonk KL,Abdul-Karim FW,Valentine M,Seachrist DD,Grennel-Nickelson KE,Cuellar-Vite L,Sizemore GM,Sizemore ST,Webb BM,Thompson CL,Keri RA
Tue Apr 04 00:00:00 UTC 2023
Pharmacological modulation of RORα controls fat browning, adaptive thermogenesis, and body weight in mice.
American journal of physiology. Endocrinology and metabolism
Auclair M,Roblot N,Capel E,Fève B,Antoine B
Mon Feb 01 00:00:00 UTC 2021
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination.
Cell reports
Wang Y,Zhang Y,Zhang S,Kim B,Hull VL,Xu J,Prabhu P,Gregory M,Martinez-Cerdeno V,Zhan X,Deng W,Guo F
Tue Oct 05 00:00:00 UTC 2021
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Cell stem cell
Li Q,Sun Y,Jarugumilli GK,Liu S,Dang K,Cotton JL,Xiol J,Chan PY,DeRan M,Ma L,Li R,Zhu LJ,Li JH,Leiter AB,Ip YT,Camargo FD,Luo X,Johnson RL,Wu X,Mao J
Thu May 07 00:00:00 UTC 2020
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1.
The Journal of clinical investigation
Wang L,Xu M,Kao CY,Tsai SY,Tsai MJ
Wed Apr 01 00:00:00 UTC 2020
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1.
The Journal of clinical investigation
Wang L,Xu M,Kao CY,Tsai SY,Tsai MJ
Wed Apr 01 00:00:00 UTC 2020
Defining the proteolytic landscape during enterovirus infection.
PLoS pathogens
Saeed M,Kapell S,Hertz NT,Wu X,Bell K,Ashbrook AW,Mark MT,Zebroski HA,Neal ML,Flodström-Tullberg M,MacDonald MR,Aitchison JD,Molina H,Rice CM
Tue Sep 01 00:00:00 UTC 2020
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Acta pharmacologica Sinica
Ren Y,Xu X,Mao CY,Han KK,Xu YJ,Cao BY,Zhang ZB,Sethi G,Tang XW,Mao XL
Sun Mar 01 00:00:00 UTC 2020
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer.
Nature
Parolia A,Cieslik M,Chu SC,Xiao L,Ouchi T,Zhang Y,Wang X,Vats P,Cao X,Pitchiaya S,Su F,Wang R,Feng FY,Wu YM,Lonigro RJ,Robinson DR,Chinnaiyan AM
Mon Jul 01 00:00:00 UTC 2019
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer.
Nature
Parolia A,Cieslik M,Chu SC,Xiao L,Ouchi T,Zhang Y,Wang X,Vats P,Cao X,Pitchiaya S,Su F,Wang R,Feng FY,Wu YM,Lonigro RJ,Robinson DR,Chinnaiyan AM
Mon Jul 01 00:00:00 UTC 2019
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer.
Nature
Parolia A,Cieslik M,Chu SC,Xiao L,Ouchi T,Zhang Y,Wang X,Vats P,Cao X,Pitchiaya S,Su F,Wang R,Feng FY,Wu YM,Lonigro RJ,Robinson DR,Chinnaiyan AM
Mon Jul 01 00:00:00 UTC 2019
Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity.
Oncotarget
Ogawa M,Yaginuma T,Nakatomi C,Nakajima T,Tada-Shigeyama Y,Addison WN,Urata M,Matsubara T,Watanabe K,Matsuo K,Sato T,Honda H,Hikiji H,Watanabe S,Kokabu S
Tue Jan 08 00:00:00 UTC 2019
Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity.
Oncotarget
Ogawa M,Yaginuma T,Nakatomi C,Nakajima T,Tada-Shigeyama Y,Addison WN,Urata M,Matsubara T,Watanabe K,Matsuo K,Sato T,Honda H,Hikiji H,Watanabe S,Kokabu S
Tue Jan 08 00:00:00 UTC 2019
Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity.
Oncotarget
Ogawa M,Yaginuma T,Nakatomi C,Nakajima T,Tada-Shigeyama Y,Addison WN,Urata M,Matsubara T,Watanabe K,Matsuo K,Sato T,Honda H,Hikiji H,Watanabe S,Kokabu S
Tue Jan 08 00:00:00 UTC 2019
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism.
Genes & development
Pearson S,Loft A,Rajbhandari P,Simcox J,Lee S,Tontonoz P,Mandrup S,Villanueva CJ
Mon Jul 01 00:00:00 UTC 2019
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism.
Genes & development
Pearson S,Loft A,Rajbhandari P,Simcox J,Lee S,Tontonoz P,Mandrup S,Villanueva CJ
Mon Jul 01 00:00:00 UTC 2019
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism.
Genes & development
Pearson S,Loft A,Rajbhandari P,Simcox J,Lee S,Tontonoz P,Mandrup S,Villanueva CJ
Mon Jul 01 00:00:00 UTC 2019
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism.
Genes & development
Pearson S,Loft A,Rajbhandari P,Simcox J,Lee S,Tontonoz P,Mandrup S,Villanueva CJ
Mon Jul 01 00:00:00 UTC 2019
Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.
The Journal of experimental medicine
Xing S,Shao P,Li F,Zhao X,Seo W,Wheat JC,Ramasamy S,Wang J,Li X,Peng W,Yu S,Liu C,Taniuchi I,Sweetser DA,Xue HH
Mon Aug 06 00:00:00 UTC 2018
Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.
The Journal of experimental medicine
Xing S,Shao P,Li F,Zhao X,Seo W,Wheat JC,Ramasamy S,Wang J,Li X,Peng W,Yu S,Liu C,Taniuchi I,Sweetser DA,Xue HH
Mon Aug 06 00:00:00 UTC 2018
The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor.
The Journal of biological chemistry
Kokabu S,Nakatomi C,Matsubara T,Ono Y,Addison WN,Lowery JW,Urata M,Hudnall AM,Hitomi S,Nakatomi M,Sato T,Osawa K,Yoda T,Rosen V,Jimi E
Fri Aug 04 00:00:00 UTC 2017
The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor.
The Journal of biological chemistry
Kokabu S,Nakatomi C,Matsubara T,Ono Y,Addison WN,Lowery JW,Urata M,Hudnall AM,Hitomi S,Nakatomi M,Sato T,Osawa K,Yoda T,Rosen V,Jimi E
Fri Aug 04 00:00:00 UTC 2017
The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor.
The Journal of biological chemistry
Kokabu S,Nakatomi C,Matsubara T,Ono Y,Addison WN,Lowery JW,Urata M,Hudnall AM,Hitomi S,Nakatomi M,Sato T,Osawa K,Yoda T,Rosen V,Jimi E
Fri Aug 04 00:00:00 UTC 2017
The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor.
The Journal of biological chemistry
Kokabu S,Nakatomi C,Matsubara T,Ono Y,Addison WN,Lowery JW,Urata M,Hudnall AM,Hitomi S,Nakatomi M,Sato T,Osawa K,Yoda T,Rosen V,Jimi E
Fri Aug 04 00:00:00 UTC 2017
Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression.
Journal of molecular medicine (Berlin, Germany)
Ortega FJ,Serrano M,Rodriguez-Cuenca S,Moreno-Navarrete JM,Gómez-Serrano M,Sabater M,Rodriguez-Hermosa JI,Xifra G,Ricart W,Peral B,Vidal-Puig A,Fernández-Real JM
Thu Jan 01 00:00:00 UTC 2015
Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression.
Journal of molecular medicine (Berlin, Germany)
Ortega FJ,Serrano M,Rodriguez-Cuenca S,Moreno-Navarrete JM,Gómez-Serrano M,Sabater M,Rodriguez-Hermosa JI,Xifra G,Ricart W,Peral B,Vidal-Puig A,Fernández-Real JM
Thu Jan 01 00:00:00 UTC 2015
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.
Cell metabolism
Villanueva CJ,Vergnes L,Wang J,Drew BG,Hong C,Tu Y,Hu Y,Peng X,Xu F,Saez E,Wroblewski K,Hevener AL,Reue K,Fong LG,Young SG,Tontonoz P
Tue Mar 05 00:00:00 UTC 2013
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.
Cell metabolism
Villanueva CJ,Vergnes L,Wang J,Drew BG,Hong C,Tu Y,Hu Y,Peng X,Xu F,Saez E,Wroblewski K,Hevener AL,Reue K,Fong LG,Young SG,Tontonoz P
Tue Mar 05 00:00:00 UTC 2013
Cross-regulation between FOXA1 and ErbB2 signaling in estrogen receptor-negative breast cancer.
Neoplasia (New York, N.Y.)
Naderi A,Meyer M,Dowhan DH
Sun Apr 01 00:00:00 UTC 2012
Cross-regulation between FOXA1 and ErbB2 signaling in estrogen receptor-negative breast cancer.
Neoplasia (New York, N.Y.)
Naderi A,Meyer M,Dowhan DH
Sun Apr 01 00:00:00 UTC 2012
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Cell metabolism
Villanueva CJ,Waki H,Godio C,Nielsen R,Chou WL,Vargas L,Wroblewski K,Schmedt C,Chao LC,Boyadjian R,Mandrup S,Hevener A,Saez E,Tontonoz P
Wed Apr 06 00:00:00 UTC 2011
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Cell metabolism
Villanueva CJ,Waki H,Godio C,Nielsen R,Chou WL,Vargas L,Wroblewski K,Schmedt C,Chao LC,Boyadjian R,Mandrup S,Hevener A,Saez E,Tontonoz P
Wed Apr 06 00:00:00 UTC 2011
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Cell metabolism
Villanueva CJ,Waki H,Godio C,Nielsen R,Chou WL,Vargas L,Wroblewski K,Schmedt C,Chao LC,Boyadjian R,Mandrup S,Hevener A,Saez E,Tontonoz P
Wed Apr 06 00:00:00 UTC 2011
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Cell metabolism
Villanueva CJ,Waki H,Godio C,Nielsen R,Chou WL,Vargas L,Wroblewski K,Schmedt C,Chao LC,Boyadjian R,Mandrup S,Hevener A,Saez E,Tontonoz P
Wed Apr 06 00:00:00 UTC 2011