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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPPPPPLSCL RGLQAPHQPG QPGFKFTVAE SCDRIKDEFQ FLQAQYHSLK VEYDKLANEK TEMQRHYVMY YEMSYGLNIE MHKQTEIAKR LNTILAQIMP FLSQEHQQQV AQAVERAKQV TMTELNAIIG QQLQAQHLSH ATHGPPVQLP PHPSGLQPPG IPPVTGSSSG LLALGALGSQ AHLTVKDEKN HHELDHRERE SSANNSVSPS ESLRASEKHR GSADYSMEAK KRKAEEKDSL SRYDSDGDKS DDLVVDVSNE DPATPRVSPA HSPPENGLDK ARSLKKDAPT SPASVASSSS TPSSKTKDLG HNDKSSTPGL KSNTPTPRND APTPGTSTTP GLRSMPGKPP GMDPIGIMAS ALRTPISITS SYAAPFAMMS HHEMNGSLTS PGAYAGLHNI PPQMSAAAAA AAATYGRSPM VGFDPHPPMR ATGLPSSLAS IPGGKPAYSF HVSADGQMQP VPFPHDALAG PGIPRHARQI NTLSHGEVVC AVTISNPTRH VYTGGKGCVK IWDISQPGSK SPISQLDCLN RDNYIRSCKL LPDGRTLIVG GEASTLTIWD LASPTPRIKA ELTSSAPACY ALAISPDAKV CFSCCSDGNI AVWDLHNQTL VRQFQGHTDG ASCIDISHDG TKLWTGGLDN TVRSWDLREG RQLQQHDFTS QIFSLGYCPT GEWLAVGMES SNVEVLHHTK PDKYQLHLHE SCVLSLKFAY CGKWFVSTGK DNLLNAWRTP YGASIFQSKE SSSVLSCDIS ADDKYIVTGS GDKKATVYEV IY
The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: enhancer of split groucho 3; Enhancer of split groucho-like protein 3; ESG-1; ESG-2; ESG-3; ESG-4; ESG3; Tle1; Tle2; tle4; transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3 short isoform; transducin-like enhancer of split 3, homolog of Drosophila E(sp1); Transducin-like enhancer protein 3
Gene Aliases: ESG; ESG3; GRG3; HsT18976; KIAA1547; TLE3
UniProt ID: (Human) Q04726
Entrez Gene ID: (Human) 7090
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