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Bioss
TLE4 Polyclonal Antibody
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Product Details
BS-12403R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TLE4, amino acids 681-773.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B lymphocyte gene 1; enhancer of split groucho 4; Grg-4; Groucho-related protein 4; Protein ESP2; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, E(spl) homolog; transducin-like enhancer of split 4, homolog of Drosophila E(sp1); transducin-like enhancer of split 4, homolog of Drosophila E(spl); Transducin-like enhancer protein 4
Gene Aliases: 5730411M05Rik; AA792082; BCE-1; BCE1; E(spI); ESG; ESG4; Esp2; ESTM13; ESTM14; Grg-4; GRG4; KIAA1261; TLE4; X83332; X83333
UniProt ID: (Human) Q04727, (Mouse) Q62441, (Rat) Q07141
Entrez Gene ID: (Human) 7091, (Mouse) 21888, (Rat) 25565
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
biological_process
Wnt signaling pathway
beta-catenin-TCF complex assembly
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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