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Invitrogen
TLE4 Polyclonal Antibody
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FIGURE: 1 / 1
TLE4 Antibody (PA5-110491) in WB
Western blot analysis of TLE4 in extracts of Rat lung. Samples were incubated with TLE4 Polyclonal antibody (Product # PA5-110491) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-110491
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 173-243 of human TLE4 (NP_001269677)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855902
Product Specific Information
Immunogen sequence: SSALGGQSHL PIKDEKKHHD NDHQRDRDSI KSSSVSPSAS FRGAEKHRNS ADYSSESKKQ KTEEKEIAAR Y
Target Information
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Grg-4; Groucho-related protein 4; Protein ESP2; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, E(spl) homolog; transducin-like enhancer of split 4, homolog of Drosophila E(spl); Transducin-like enhancer protein 4
Gene Aliases: Esp2; Grg-4; Grg4; Tle4
UniProt ID: (Rat) Q07141
Entrez Gene ID: (Rat) 25565
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Wnt signaling pathway
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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