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Rockland
TMBIM1 Polyclonal Antibody
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Product Details
200-401-A57
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Protein A
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is specific for human TMBIM1 protein. A BLAST analysis was used to suggest partial cross-reactivity with TMBIM1 from mouse and rat sources based on ~88% homology with the immunizing sequence. Cross-reactivity with TMBIM1 from other sources has not been determined.
Target Information
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1
Gene Aliases: LFG3; MST100; MSTP100; PP1201; PSEC0158; RECS1; TMBIM1
UniProt ID: (Human) Q969X1
Entrez Gene ID: (Human) 64114
negative regulation of catalytic activity
negative regulation of establishment of protein localization to plasma membrane
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of Fas signaling pathway
positive regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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