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Invitrogen
TMBIM1 Polyclonal Antibody
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FIGURE: 1 / 3
TMBIM1 Antibody (PA5-101938) in ICC/IF
Immunocytochemistry analysis of TMBIM1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with TMBIM1 polyclonal antibody (Product # PA5-101938) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-101938
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TMBIM1(Accession Q969X1), corresponding to amino acid residues M251-T301.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851370
Product Specific Information
Antibody detects endogenous levels of total TMBIM1.
Target Information
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein lifeguard 3; Protein RECS1; Protein RECS1 homolog; Responsive to centrifugal force and shear stress gene 1 protein; Transmembrane BAX inhibitor motif-containing protein 1
Gene Aliases: 2310061B02Rik; AA960455; AU024746; C78899; LFG3; mKIAA4161; MST100; MSTP100; PP1201; PSEC0158; RECS1; Tmbib1; TMBIM1
UniProt ID: (Human) Q969X1, (Mouse) Q8BJZ3
Entrez Gene ID: (Human) 64114, (Mouse) 69660, (Rat) 316516
negative regulation of catalytic activity
negative regulation of establishment of protein localization to plasma membrane
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of Fas signaling pathway
positive regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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