Proteintech

TMED9 Polyclonal Antibody

TMED9 Antibody in Immunocytochemistry (ICC/IF)

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TMED9 Antibody (21620-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using TMED9 antibody (Product # 21620-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red).

TMED9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

TMED9 Antibody in Immunoprecipitation (IP)

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Product Details

21620-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TMED9 Fusion Protein Ag13813 (1-224 aa encoded by BC001123)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAVELGVLL VRPRPGTGLG RVMRTLLLVL WLATRGSALY FHIGETEKKC FIEEIPDETM VIGNYRTQLY DKQREEYQPA TPGLGMFVEV KDPEDKVILA RQYGSEGRFT FTSHTPGEHQ ICLHSNSTKF SLFAGGMLRV HLDIQVGEHA NDYAEIAAKD KLSELQLRVR QLVEQVEQIQ KEQNYQRWRE ERFRQTSEST NQRVLWWSIL QTLILVAIGV WQMRH (1-224 aa encoded by BC001123)

Target Information

TMED9 (also named as GMP25, GP25L2 or p25) is a member of the EMP24/GP25L family. TMED9 probably forms hetero-oligomeric complexes with TMED7 (p27), TMED2 (p24), and TMED10 (p23). Located in the endoplasmic reticulum and the Golgi, TMED9 appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Park H,Seo SK,Sim JR,Hwang SJ,Kim YJ,Shin DH,Jang DG,Noh SH,Park PG,Ko SH,Shin MH,Choi JY,Ito Y,Kang CM,Lee JM,Lee MG

Mon Aug 01 00:00:00 UTC 2022

Screening of the novel immune-suppressive biomarkers of TMED family and whether knockdown of TMED2/3/4/9 inhibits cell migration and invasion in breast cancer.

Annals of translational medicine

Fang Z,Song YX,Wo GQ,Zhou HL,Li L,Yang SY,Chen X,Zhang J,Tang JH

Thu Dec 01 00:00:00 UTC 2022

A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.

Cell research

Li S,Yan R,Xu J,Zhao S,Ma X,Sun Q,Zhang M,Li Y,Liu JG,Chen L,Li S,Xu K,Ge L

Tue Feb 01 00:00:00 UTC 2022

A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.

Cell research

Li S,Yan R,Xu J,Zhao S,Ma X,Sun Q,Zhang M,Li Y,Liu JG,Chen L,Li S,Xu K,Ge L

Tue Feb 01 00:00:00 UTC 2022

ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.

BMC biology

Yue X,Qian Y,Zhu L,Gim B,Bao M,Jia J,Jing S,Wang Y,Tan C,Bottanelli F,Ziltener P,Choi S,Hao P,Lee I

Tue Sep 07 00:00:00 UTC 2021

High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.

Bioengineered

Ju G,Xu C,Zeng K,Zhou T,Zang L

Wed Dec 01 00:00:00 UTC 2021

High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.

Bioengineered

Ju G,Xu C,Zeng K,Zhou T,Zang L

Wed Dec 01 00:00:00 UTC 2021

A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.

Cell

Zhang M,Liu L,Lin X,Wang Y,Li Y,Guo Q,Li S,Sun Y,Tao X,Zhang D,Lv X,Zheng L,Ge L

Thu Apr 30 00:00:00 UTC 2020

Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.

Cell

Dvela-Levitt M,Kost-Alimova M,Emani M,Kohnert E,Thompson R,Sidhom EH,Rivadeneira A,Sahakian N,Roignot J,Papagregoriou G,Montesinos MS,Clark AR,McKinney D,Gutierrez J,Roth M,Ronco L,Elonga E,Carter TA,Gnirke A,Melanson M,Hartland K,Wieder N,Hsu JC,Deltas C,Hughey R,Bleyer AJ,Kmoch S,Živná M,Barešova V,Kota S,Schlondorff J,Heiman M,Alper SL,Wagner F,Weins A,Golub TR,Lander ES,Greka A

Thu Jul 25 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: Glycoprotein 25L2; GMP25; gp25L2 protein; p24 family protein alpha-2; p24alpha2; p25; Transmembrane emp24 domain-containing protein 9; transmembrane emp24 protein transport domain containing 9

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Gene Aliases: 2400003B06Rik; GMP25; GP25L2; HSGP25L2G; p24a2; p25; RGD1307627; TMED9

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UniProt ID: (Human) Q9BVK6, (Rat) Q5I0E7, (Mouse) Q99KF1

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Entrez Gene ID: (Human) 54732, (Rat) 361207, (Mouse) 67511

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Function(s)

protein binding syntaxin binding

Process(es)

Golgi organization positive regulation of organelle organization protein transport protein exit from endoplasmic reticulum early endosome to Golgi transport COPI coating of Golgi vesicle ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TMED9 Polyclonal Antibody

TMED9 Antibody (21620-1-AP) in ICC/IF

Product Details

21620-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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