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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TMEM106B Antibodies

          Invitrogen

          TMEM106B Polyclonal Antibody

          Advanced Verification
          2 Published Figures
          2 References
          View all (8) TMEM106B antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
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          Cite TMEM106B Polyclonal Antibody

          • Antibody Testing Data (7)
          • Published Figures (2)
          • Advanced Verification (1)
          TMEM106B Antibody in Immunocytochemistry (ICC/IF)
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          TMEM106B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          TMEM106B Antibody (PA5-63558) in ICC/IF

          Immunofluorescent staining of TMEM106B in human cell line A549 using a TMEM106B Polyclonal Antibody (Product # PA5-63558) shows localization to endosomes and lysosomes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          TMEM106B Antibody in Immunocytochemistry (ICC/IF)
          TMEM106B Antibody in Immunohistochemistry (IHC)
          TMEM106B Antibody in Immunohistochemistry (IHC)
          TMEM106B Antibody in Immunohistochemistry (IHC)
          TMEM106B Antibody in Immunohistochemistry (IHC)
          TMEM106B Antibody in Western Blot (WB)
          TMEM106B Antibody in Immunoprecipitation (IP)
          TMEM106B Antibody in Western Blot (WB)
          TMEM106B Antibody in Western Blot, Immunoprecipitation (WB, IP)
          TMEM106B Antibody

          Product Details

          PA5-63558

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          Immunoprecipitation (IP)

          Assay-dependent
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human TMEM106B. Recombinant protein control fragment (Product #RP-100479).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.08 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2648556

          Product Specific Information

          Immunogen sequence: GKSLSHLPLH SSKEDAYDGV TSENMRNGLV NSEVHNEDGR NGDVSQFPYV EF

          Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 87%.

          Target Information

          Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Transmembrane protein 106B

          View more View less

          Gene Aliases: TMEM106B

          View more View less

          UniProt ID: (Human) Q9NUM4

          View more View less

          Entrez Gene ID: (Human) 54664

          View more View less

          Function(s)
          molecular_function protein binding
          Process(es)
          lysosome organization lysosomal transport lysosome localization dendrite morphogenesis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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