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Immunogen sequence: MGKSLSHLP LHSSKEDAYD GVTSENMRNG LVNSEVHNED GRNGDVS (1-46 aa encoded by B C033901)
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Transmembrane protein 106B
Gene Aliases: TMEM106B
UniProt ID: (Human) Q9NUM4
Entrez Gene ID: (Human) 54664
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