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Product Details
PA5-102247
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TMEM185A(Accession Q8NFB2), corresponding to amino acid residues D298-M348.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851664
Product Specific Information
Antibody detects endogenous levels of total TMEM185A.
Target Information
The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ee3; erythropoietin-induced EST 3; family with sequence similarity 11, member A; fragile site, folic acid type, rare, fra(X)(q28) F; Protein FAM11A; Transmembrane protein 185A
Gene Aliases: CXorf13; ee3; FAM11A; FRAXF; TMEM185A
UniProt ID: (Human) Q8NFB2
Entrez Gene ID: (Mouse) 236848, (Human) 84548
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