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Invitrogen
TMEM255B Polyclonal Antibody
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FIGURE: 1 / 3
TMEM255B Antibody (PA5-118316) in ICC/IF
Immunofluorescence staining of FAM70B in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with TMEM255B Polyclonal Antibody (Product # PA5-118316, 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus.
Product Details
PA5-118316
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human TMEM255B/FAM70B fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2902911
Product Specific Information
Specificity: Human TMEM255B
Target Information
The TMEM255B gene encodes a member of the transmembrane protein family, which are proteins that span biological membranes and have been suggested to have roles in cellular signaling and structure. TMEM255B has been studied for its expression in different cancer types, where it acts as a potential marker. Specifically, it has been observed in serous cystic neoplasms (SCNs) and other neoplasms, with a noteworthy frequency in gastric-type intraductal papillary mucinous neoplasms (IPMNs) and pancreatic ductal adenocarcinomas (PDACs). The expression of TMEM255B in these neoplasms indicates its potential as a diagnostic marker and may reflect its involvement in cancer biology. While its functions are still being elucidated, TMEM255B's role in cancer highlights its significance in tumor progression and potential as a target for further investigation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 70, member B; Protein FAM70B; Transmembrane protein 255B
Gene Aliases: FAM70B; TMEM255B
UniProt ID: (Human) Q8WV15
Entrez Gene ID: (Human) 348013
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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