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Product Details
PA5-42844
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human TMEM48
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2605724
Product Specific Information
Peptide sequence: SFTEDRFGVV QTTLPAILNT LLTLQEAVDK YFKLPHASSK PPRISGSLVD
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Target Information
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ10407; FLJ12556; FLJ34120; hNDC1; nuclear division cycle 1 homolog; Nucleoporin NDC1; RP4-654H19.1; Transmembrane protein 48
Gene Aliases: NDC1; NET3; TMEM48
UniProt ID: (Human) Q9BTX1
Entrez Gene ID: (Human) 55706
mRNA export from nucleus
tRNA export from nucleus
mitotic nuclear envelope disassembly
synapsis
spermatogenesis
regulation of glucose transport
protein transport
viral process
protein sumoylation
viral transcription
spindle pole body duplication
gene silencing by RNA
nuclear pore distribution
nuclear pore complex assembly
establishment of spindle pole body localization to nuclear envelope
intracellular transport of virus
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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