Proteintech

TMOD1 Polyclonal Antibody

FIGURE: 1 / 5

TMOD1 Antibody (10145-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 10145-1-AP) TMOD1 antibody at dilution of 1:3,000 incubated at room temperature for 1.5 hours.

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Product Details

10145-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

Assay-dependent

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TMOD1 Fusion Protein Ag0192 (105-359 aa encoded by BC002660)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PVLESVTLE PELEEALANA SDAELCDIAA ILGMHTLMSN QQYYQALSSS SIMNKEGLNS VIKPTQYKPV PDEEPNSTDV EETLERIKNN DPKLEEVNLN NIRNIPIPTL KAYAEALKEN SYVKKFSIVG TRSNDPVAYA LAEMLKENKV LKTLNVESNF ISGAGILRLV EALPYNTSLV EMKIDNQSQP LGNKVEMEIV SMLEKNATLL KFGYHFTQQG PRLRASNAMM NNNDLVRKRR LADLTGPIIP KCRSGV (105-359 aa encoded by BC002660)

Target Information

TMOD1 gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.

The Journal of biological chemistry

Ushijima T,Fujimoto N,Matsuyama S,Kan-O M,Kiyonari H,Shioi G,Kage Y,Yamasaki S,Takeya R,Sumimoto H

Fri Jan 05 00:00:00 UTC 2018

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.

The Journal of biological chemistry

Ushijima T,Fujimoto N,Matsuyama S,Kan-O M,Kiyonari H,Shioi G,Kage Y,Yamasaki S,Takeya R,Sumimoto H

Fri Jan 05 00:00:00 UTC 2018

S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination.

Glia

Dukala DE,Soliven B

Fri Apr 01 00:00:00 UTC 2016

S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination.

Glia

Dukala DE,Soliven B

Fri Apr 01 00:00:00 UTC 2016

Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis.

PloS one

Fujimoto N,Kan-O M,Ushijima T,Kage Y,Tominaga R,Sumimoto H,Takeya R

Tue Jul 19 00:00:00 UTC 2016

Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis.

PloS one

Fujimoto N,Kan-O M,Ushijima T,Kage Y,Tominaga R,Sumimoto H,Takeya R

Tue Jul 19 00:00:00 UTC 2016

Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart.

PloS one

Kan-o M,Takeya R,Taniguchi K,Tanoue Y,Tominaga R,Sumimoto H

Tue Aug 07 00:00:00 UTC 2012

Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart.

PloS one

Kan-o M,Takeya R,Taniguchi K,Tanoue Y,Tominaga R,Sumimoto H

Tue Aug 07 00:00:00 UTC 2012

Identification of a unique gene expression signature that differentiates hepatocellular adenoma from well-differentiated hepatocellular carcinoma.

The American journal of surgical pathology

Chen ZM,Crone KG,Watson MA,Pfeifer JD,Wang HL

Thu Dec 01 00:00:00 UTC 2005

Identification of a unique gene expression signature that differentiates hepatocellular adenoma from well-differentiated hepatocellular carcinoma.

The American journal of surgical pathology

Chen ZM,Crone KG,Watson MA,Pfeifer JD,Wang HL

Thu Dec 01 00:00:00 UTC 2005

Bioinformatics

Protein Aliases: E tropomodulin 1; E-Tmod; E-Tropomodulin; Erythrocyte tropomodulin; Tropomodulin-1

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Gene Aliases: D9S57E; E-Tmod; ETMOD; TMOD; TMOD1

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UniProt ID: (Human) P28289, (Mouse) P49813

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Entrez Gene ID: (Human) 7111, (Mouse) 21916, (Rat) 25566

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Function(s)

actin binding tropomyosin binding actin filament binding

Process(es)

muscle contraction actin filament organization adult locomotory behavior myofibril assembly skeletal muscle myosin thick filament assembly pointed-end actin filament capping muscle filament sliding lens fiber cell development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TMOD1 Polyclonal Antibody

TMOD1 Antibody (10145-1-AP) in WB

Product Details

10145-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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