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Proteintech
TMPRSS3 Polyclonal Antibody
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Product Details
17953-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMPRSS3 Fusion Protein Ag12435 (262-453 aa encoded by BC074846)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDGKVCWT SGWGATEDGG DASPVLNHAA VPLISNKICN HRDVYGGIIS PSMLCAGYLT GGVDSCQGDS GGPLVCQERR LWKLVGATSF GIGCAEVNKP GVYTRVTSFL DWIHEQMERD LKT (262-453 aa encoded by BC074846)
Target Information
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Serine protease TADG-12; Transmembrane protease serine 3; transmembrane proteinase serine 3; Tumor-associated differentially-expressed gene 12 protein
Gene Aliases: DFNB10; DFNB8; ECHOS1; TADG12; TMPRSS3; UNQ323/PRO382
UniProt ID: (Human) P57727, (Mouse) Q8K1T0
Entrez Gene ID: (Human) 64699, (Mouse) 140765, (Rat) 309665
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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