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This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: CAPH2; Channel-activating protease 2; Channel-activating protease 4; mCAP2; Membrane-type serine protease 2; MT-SP2; Transmembrane protease serine 4; transmembrane serine protease 3; type II membrane serine protease
Gene Aliases: Cap2; CAPH2; mCAP2; MT-SP2; TMPRSS3; TMPRSS4; UNQ776/PRO1570
UniProt ID: (Human) Q9NRS4, (Mouse) Q8VCA5
Entrez Gene ID: (Human) 56649, (Rat) 367074, (Mouse) 214523
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