Product References
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Nature immunology
Linnerbauer M,Lößlein L,Vandrey O,Peter A,Han Y,Tsaktanis T,Wogram E,Needhamsen M,Kular L,Nagel L,Zissler J,Andert M,Meszaros L,Hanspach J,Zuber F,Naumann UJ,Diebold M,Wheeler MA,Beyer T,Nirschl L,Cirac A,Laun FB,Günther C,Winkler J,Bäuerle T,Jagodic M,Hemmer B,Prinz M,Quintana FJ,Rothhammer V
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Journal of biomedical science
Li P,Zhou D,Chen D,Cheng Y,Chen Y,Lin Z,Zhang X,Huang Z,Cai J,Huang W,Lin Y,Ke H,Long J,Zou Y,Ye S,Lan P
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Jun 28 00:00:00 UTC 2023
Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke.
Journal of neuroinflammation
Liu PY,Li HQ,Dong MQ,Gu XY,Xu SY,Xia SN,Bao XY,Xu Y,Cao X
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sat Nov 11 00:00:00 UTC 2023
Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma.
International journal of molecular sciences
Sieow JL,Penny HL,Gun SY,Tan LQ,Duan K,Yeong JPS,Pang A,Lim D,Toh HC,Lim TKH,Engleman E,Rotzschke O,Ng LG,Chen J,Tan SM,Wong SC
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2023
Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice.
Aging and disease
Elsayed R,Elashiry M,Liu Y,Morandini AC,El-Awady A,Elashiry MM,Hamrick M,Cutler CW
11-7321-82 was used in Flow cytometry/Cell sorting to conclude that immune senescence, compounded by advanced age, and accelerated by oral dysbiosis and its induced SASP exosomes, plays a pivotal role in the pathophysiology of experimental periodontitis.
Wed Feb 01 00:00:00 UTC 2023
Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis.
JCI insight
Ma N,Yuan C,Shi J,Zhu Q,Liu Y,Ma X,Li B,Gong W,Xue J,Lu G,Li W,Li J
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Tue Nov 08 00:00:00 UTC 2022
Translation factor eIF5a is essential for IFNγ production and cell cycle regulation in primary CD8+ T lymphocytes.
Nature communications
Tan TCJ,Kelly V,Zou X,Wright D,Ly T,Zamoyska R
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sat Dec 17 00:00:00 UTC 2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
JCI insight
Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Apr 08 00:00:00 UTC 2022
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Cancer cell
Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D
11-7321-82 was used in flow cytometry to assess this concept by combining vascular endothelial growth factor (VEGF) pathway inhibitors that remodel the tumor vasculature with the tricyclic antidepressant imipramine, which enhances autophagy in GBM cancer cells and unexpectedly reprograms immunosuppressive tumor-associated macrophages via inhibition of histamine receptor signaling to become immunostimulatory.
Mon Oct 10 00:00:00 UTC 2022
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Cancer cell
Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D
11-7321-82 was used in flow cytometry to assess this concept by combining vascular endothelial growth factor (VEGF) pathway inhibitors that remodel the tumor vasculature with the tricyclic antidepressant imipramine, which enhances autophagy in GBM cancer cells and unexpectedly reprograms immunosuppressive tumor-associated macrophages via inhibition of histamine receptor signaling to become immunostimulatory.
Mon Oct 10 00:00:00 UTC 2022
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling.
Nature communications
Xie F,Zhou X,Su P,Li H,Tu Y,Du J,Pan C,Wei X,Zheng M,Jin K,Miao L,Wang C,Meng X,van Dam H,Ten Dijke P,Zhang L,Zhou F
11-7321-82 was used in Flow Cytometry to investigate TβRII and extracellular vesicle delivery in breast cancer to derive targets for immunotherapy.
Mon Aug 01 00:00:00 UTC 2022
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling.
Nature communications
Xie F,Zhou X,Su P,Li H,Tu Y,Du J,Pan C,Wei X,Zheng M,Jin K,Miao L,Wang C,Meng X,van Dam H,Ten Dijke P,Zhang L,Zhou F
11-7321-82 was used in Flow Cytometry to investigate TβRII and extracellular vesicle delivery in breast cancer to derive targets for immunotherapy.
Mon Aug 01 00:00:00 UTC 2022
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
International journal of molecular sciences
Yang G,Wang J,Wang S,Zhu Y
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sat Aug 20 00:00:00 UTC 2022
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
International journal of molecular sciences
Zou Y,Wang X,Xu J,Wang S,Li S,Zhu Y,Wang J
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Oct 31 00:00:00 UTC 2022
Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung.
Nature communications
Horn KJ,Schopper MA,Drigot ZG,Clark SE
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Jun 09 00:00:00 UTC 2022
Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies.
Theranostics
Li H,Peng K,Yang K,Ma W,Qi S,Yu X,He J,Lin X,Yu G
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Sep 29 00:00:00 UTC 2022
Imprint of Initial Education and Loss of Ly49C/I in Activated Natural Killer Cells of TAP1-KO and C57BL/6 Wildtype Mice.
Frontiers in immunology
Patil ND,Domingues O,Masquelier C,Theresine M,Schlienger O,Njinju Amin Asaba C,Thomas M,Seguin-Devaux C,Slevogt H,Ollert M,Zimmer J
11-7321-82 was used in Flow cytometry/Cell sorting to show that we completed our investigations with phenotypic studies of NK cells from these mice.
Tue Aug 02 00:00:00 UTC 2022
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.
Nature
Zheng J,Wong LR,Li K,Verma AK,Ortiz ME,Wohlford-Lenane C,Leidinger MR,Knudson CM,Meyerholz DK,McCray PB,Perlman S
11-7321 was used in Flow cytometry/Cell sorting to show that K18-hACE2 mice provide a useful model for studying the pathological basis of both mild and lethal COVID-19 and for assessing therapeutic interventions.
Fri Jan 01 00:00:00 UTC 2021
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.
Nature
Zheng J,Wong LR,Li K,Verma AK,Ortiz ME,Wohlford-Lenane C,Leidinger MR,Knudson CM,Meyerholz DK,McCray PB,Perlman S
11-7321 was used in Flow cytometry/Cell sorting to show that K18-hACE2 mice provide a useful model for studying the pathological basis of both mild and lethal COVID-19 and for assessing therapeutic interventions.
Fri Jan 01 00:00:00 UTC 2021
The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity.
Nature immunology
Zhou J,Kryczek I,Li S,Li X,Aguilar A,Wei S,Grove S,Vatan L,Yu J,Yan Y,Liao P,Lin H,Li J,Li G,Du W,Wang W,Lang X,Wang W,Wang S,Zou W
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Mapping and role of T cell response in SARS-CoV-2-infected mice.
The Journal of experimental medicine
Zhuang Z,Lai X,Sun J,Chen Z,Zhang Z,Dai J,Liu D,Li Y,Li F,Wang Y,Zhu A,Wang J,Yang W,Huang J,Li X,Hu L,Wen L,Zhuo J,Zhang Y,Chen D,Li S,Huang S,Shi Y,Zheng K,Zhong N,Zhao J,Zhou D,Zhao J
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Apr 05 00:00:00 UTC 2021
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Molecular therapy : the journal of the American Society of Gene Therapy
Teng Y,Xu F,Zhang X,Mu J,Sayed M,Hu X,Lei C,Sriwastva M,Kumar A,Sundaram K,Zhang L,Park JW,Chen SY,Zhang S,Yan J,Merchant ML,Zhang X,McClain CJ,Wolfe JK,Adcock RS,Chung D,Palmer KE,Zhang HG
11-7321-82 was used in Flow cytometry/Cell sorting to reveal exosomesNsp12Nsp13 as potentially important contributors to the development of lung inflammation, and GELNs are a potential therapeutic agent to treat COVID-19.
Wed Aug 04 00:00:00 UTC 2021
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Molecular therapy : the journal of the American Society of Gene Therapy
Teng Y,Xu F,Zhang X,Mu J,Sayed M,Hu X,Lei C,Sriwastva M,Kumar A,Sundaram K,Zhang L,Park JW,Chen SY,Zhang S,Yan J,Merchant ML,Zhang X,McClain CJ,Wolfe JK,Adcock RS,Chung D,Palmer KE,Zhang HG
11-7321-82 was used in Flow cytometry/Cell sorting to reveal exosomesNsp12Nsp13 as potentially important contributors to the development of lung inflammation, and GELNs are a potential therapeutic agent to treat COVID-19.
Wed Aug 04 00:00:00 UTC 2021
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Oxidative medicine and cellular longevity
Luo Y,Guo J,Jia W,Wu M,Yin F,Niu G,Shih DQ,Targan SR,Zhang X
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Mar 04 00:00:00 UTC 2022
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Tue Nov 07 00:00:00 UTC 2023
M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway.
Cell death discovery
Pu J,Xu Z,Nian J,Fang Q,Yang M,Huang Y,Li W,Ge B,Wang J,Wei H
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Jul 16 00:00:00 UTC 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Dec 17 00:00:00 UTC 2021
GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure.
Cell death & disease
Yu H,Yang W,Huang J,Miao X,Wang B,Ren X,Gu Y,Wang Q,Ding X,Guo X,Qian F,Zhang Y,Xu H,Zheng L,Jin M
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Dec 16 00:00:00 UTC 2021
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Cell death & disease
Liu L,Wu Y,Wang B,Jiang Y,Lin L,Li X,Yang S
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon May 17 00:00:00 UTC 2021
Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis.
Scientific reports
AuYeung AWK,Mould RC,Stegelmeier AA,van Vloten JP,Karimi K,Woods JP,Petrik JJ,Wood GA,Bridle BW
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Tue Jul 27 00:00:00 UTC 2021
T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
JCI insight
Chun N,Ang RL,Chan M,Fairchild RL,Baldwin WM,Horwitz JK,Gelles JD,Chipuk JE,Kelliher MA,Pavlov VI,Li Y,Homann D,Heeger PS,Ting AT
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Dec 22 00:00:00 UTC 2021
Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi.
Pathogens (Basel, Switzerland)
Medina-Buelvas DM,Rodríguez-Sosa M,Vega L
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sat Nov 06 00:00:00 UTC 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Aug 11 00:00:00 UTC 2021
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.
Nature communications
Liu B,Huang J,Ashraf A,Rahaman O,Lou J,Wang L,Cai P,Wen J,Anwaar S,Liu X,Ni H,Ganguly D,Zhao J,Yang CY
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Jul 02 00:00:00 UTC 2021
Rate of Freeze Impacts the Survival and Immune Responses Post Cryoablation of Melanoma.
Frontiers in immunology
Yakkala C,Dagher J,Sempoux C,Chiang CL,Denys A,Kandalaft LE,Koppolu B,Duran R
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Dec 13 00:00:00 UTC 2021
Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen.
eLife
Deets KA,Nichols Doyle R,Rauch I,Vance RE
11-7321-82 was used in Flow cytometry/Cell sorting to investigate whether inflammasomes provide sufficient signals to activate adaptive immunity.
Thu Dec 23 00:00:00 UTC 2021
Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2.
BioMed research international
Zhao K,Tian Y,Wang J,Chen C,Pan B,Yan Z,Zhu S,Xu K
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Sep 10 00:00:00 UTC 2021
Fgr contributes to hemorrhage-induced thalamic pain by activating NF-κB/ERK1/2 pathways.
JCI insight
Huang T,Fu G,Gao J,Zhang Y,Cai W,Wu S,Jia S,Xia S,Bachmann T,Bekker A,Tao YX
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Immunohistochemistry
Thu Oct 15 00:00:00 UTC 2020
Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
NPJ vaccines
Brar G,Farhat NA,Sukhina A,Lam AK,Kim YH,Hsu T,Tong L,Lin WW,Ware CF,Blackman MA,Sun R,Wu TT
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Nov 05 00:00:00 UTC 2020
Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model.
Vaccines
Reeder SM,Reuschel EL,Bah MA,Yun K,Tursi NJ,Kim KY,Chu J,Zaidi FI,Yilmaz I,Hart RJ,Perrin B,Xu Z,Humeau L,Weiner DB,Aly ASI
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Jan 10 00:00:00 UTC 2020
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Nature communications
Toubal A,Kiaf B,Beaudoin L,Cagninacci L,Rhimi M,Fruchet B,da Silva J,Corbett AJ,Simoni Y,Lantz O,Rossjohn J,McCluskey J,Lesnik P,Maguin E,Lehuen A
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Jul 24 00:00:00 UTC 2020
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response.
Journal of neuroinflammation
Lee S,Kim S,Kang HY,Lim HR,Kwon Y,Jo M,Jeon YM,Kim SR,Kim K,Ha CM,Lee S,Kim HJ
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Neutralization
Wed Oct 14 00:00:00 UTC 2020
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia.
bioRxiv : the preprint server for biology
Zheng J,Roy Wong LY,Li K,Verma AK,Ortiz M,Wohlford-Lenane C,Leidinger MR,Knudson CM,Meyerholz DK,McCray PB,Perlman S
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that K18-hACE2 mice provide a useful model for studying the pathological underpinnings of both mild and lethal COVID-19 and for assessing therapeutic interventions.
Mon Aug 10 00:00:00 UTC 2020
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides.
Frontiers in immunology
Pfeil J,Simonetti M,Lauer U,Volkmer R,von Thülen B,Durek P,Krähmer R,Leenders F,Hamann A,Hoffmann U
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Apr 29 00:00:00 UTC 2021
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
11-7321 was used in Immunocytochemistry to indicate that CD47 blockade not only enhances the function of innate immune cells but also links to adaptive immune responses through improved APC function.
Tue Apr 14 00:00:00 UTC 2020
Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1.
eLife
Madel MB,Ibáñez L,Ciucci T,Halper J,Rouleau M,Boutin A,Hue C,Duroux-Richard I,Apparailly F,Garchon HJ,Wakkach A,Blin-Wakkach C
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed May 13 00:00:00 UTC 2020
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
11-7321 was used in Flow cytometry/Cell sorting to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 UTC 2019
Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages.
Mediators of inflammation
Wiktorowicz JE,Chowdhury IH,Stafford S,Choudhuri S,Dey N,Garg NJ
11-7321 was used in Flow cytometry/Cell sorting to capture quantitative changes in abundance and S-nitrosylated (SNO) proteome signatures.
Mon Dec 16 00:00:00 UTC 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Oct 14 00:00:00 UTC 2020
Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity.
Nature microbiology
David SC,Norton T,Tyllis T,Wilson JJ,Singleton EV,Laan Z,Davies J,Hirst TR,Comerford I,McColl SR,Paton JC,Alsharifi M
11-7321 was used in Flow cytometry/Cell sorting to provide an additional explanation for the synergistic pathogenicity of IAV and S. pneumoniae, as well as heralding the prospect of exploiting the phenomenon to develop better vaccine strategies for both pathogens.
Thu Aug 01 00:00:00 UTC 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
11-7321-82 was used in Flow Cytometry to study the intrinsic mediators that render CD8+T cells dysfunctional in the tumour microenvironment.
Wed Mar 20 00:00:00 UTC 2019
Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection.
Cell
Smith NL,Patel RK,Reynaldi A,Grenier JK,Wang J,Watson NB,Nzingha K,Yee Mon KJ,Peng SA,Grimson A,Davenport MP,Rudd BD
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that the naive CD8+ T cell pool is not as homogeneous as previously thought and offers a new framework for explaining the remarkable heterogeneity in the effector and memory T cell subsets that arise after infection.
Thu Jun 28 00:00:00 UTC 2018
Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.
Immunity
Šestan M,Marinović S,Kavazović I,Cekinović Đ,Wueest S,Turk Wensveen T,Brizić I,Jonjić S,Konrad D,Wensveen FM,Polić B
11-7321 was used in Flow cytometry/Cell sorting to study how viral infection effects insulin resistance.
Tue Jul 17 00:00:00 UTC 2018
PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8+ T-Cell-Driven Antitumor Immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research
Buchan SL,Fallatah M,Thirdborough SM,Taraban VY,Rogel A,Thomas LJ,Penfold CA,He LZ,Curran MA,Keler T,Al-Shamkhani A
11-7321 was used in Flow cytometry/Cell sorting to show that suboptimal T-cell invigoration in cancer patients undergoing treatment with PD-1 checkpoint blockers will be improved by dual PD-1 blockade and CD27 agonism.
Tue May 15 00:00:00 UTC 2018
Herpes Zoster DNA Vaccines with IL-7 and IL-33 Molecular Adjuvants Elicit Protective T Cell Immunity.
Immune network
Kim AR,Park J,Kim JH,Kwak JE,Cho Y,Lee H,Jeong M,Park SH,Shin EC
11-7321 was used in Flow cytometry/Cell sorting to evaluate the T cell immunogenicity of Herpes Zoster DNA vaccines.
Mon Oct 01 00:00:00 UTC 2018
Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury.
American journal of physiology. Renal physiology
Privratsky JR,Zhang J,Lu X,Rudemiller N,Wei Q,Yu YR,Gunn MD,Crowley SD
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Sat Sep 01 00:00:00 UTC 2018
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Feb 05 00:00:00 UTC 2018
Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain.
Molecular pain
Lee S,Shi XQ,Fan A,West B,Zhang J
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Oct 22 00:00:00 UTC 2018
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
JCI insight
Wasnik S,Rundle CH,Baylink DJ,Yazdi MS,Carreon EE,Xu Y,Qin X,Lau KW,Tang X
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Sep 06 00:00:00 UTC 2018
Lactobacillus paracasei KW3110 Prevents Blue Light-Induced Inflammation and Degeneration in the Retina.
Nutrients
Morita Y,Miwa Y,Jounai K,Fujiwara D,Kurihara T,Kanauchi O
11-7321 was used in Flow cytometry/Cell sorting to show that Lactobacillus paracasei KW3110 may have a preventive effect against degrative retinal diseases.
Sat Dec 15 00:00:00 UTC 2018
Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry.
Scientific reports
Beesetty P,Wieczerzak KB,Gibson JN,Kaitsuka T,Luu CT,Matsushita M,Kozak JA
11-7321 was used in Flow cytometry/Cell sorting to study the role of TRPM7 channel kinase as a novel modulator of blastogenesis, proliferation and store-operated calcium entry.
Wed Feb 14 00:00:00 UTC 2018
Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses.
Cell metabolism
Thwe PM,Pelgrom LR,Cooper R,Beauchamp S,Reisz JA,D'Alessandro A,Everts B,Amiel E
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Tue Sep 05 00:00:00 UTC 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
11-7321 was used in Flow cytometry/Cell sorting to determine the effect of CCR4 antagonism on human renal cell carcinoma.
Wed Mar 01 00:00:00 UTC 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Jun 05 00:00:00 UTC 2017
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Acta neuropathologica
Cantoni C,Cignarella F,Ghezzi L,Mikesell B,Bollman B,Berrien-Elliott MM,Ireland AR,Fehniger TA,Wu GF,Piccio L
11-7321 was used in Flow cytometry/Cell sorting to suggest a critical role for miR-223 in modulating myeloid-derived suppressor cell biology in experimental autoimmune encephalomyelitis and in multiple sclerosis.
Sun Jan 01 00:00:00 UTC 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Nov 20 00:00:00 UTC 2019
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma.
Oncotarget
Cho JH,Lee HJ,Ko HJ,Yoon BI,Choe J,Kim KC,Hahn TW,Han JA,Choi SS,Jung YM,Lee KH,Lee YS,Jung YJ
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Tue Apr 11 00:00:00 UTC 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Aug 03 00:00:00 UTC 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Wed Oct 11 00:00:00 UTC 2017
Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production.
International journal of molecular sciences
Tsuji R,Ikado K,Fujiwara D
11-7321 was used in Flow cytometry/Cell sorting to investigate immune-stimulatory activity of lignin-rich enzyme lignin in vivo.
Tue Dec 26 00:00:00 UTC 2017
Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.
Scientific reports
Ano Y,Ikado K,Shindo K,Koizumi H,Fujiwara D
Tue Oct 24 00:00:00 UTC 2017
T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma.
Oncoimmunology
Hilmenyuk T,Ruckstuhl CA,Hayoz M,Berchtold C,Nuoffer JM,Solanki S,Keun HC,Beavis PA,Riether C,Ochsenbein AF
11-7321 was used in Flow cytometry/Cell sorting to study T cell function in Eµ-myc transgenic mice that develop an aggressive B cell lymphoma with some similarities to human Burkitt-lymphoma.
Tue Jan 12 00:00:00 UTC 2021
CD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose.
Cellular & molecular immunology
Hu Z,Molloy MJ,Usherwood EJ
11-7321 was used in Flow cytometry/Cell sorting to investigate the role of of CD4(+) T-cell help in CD8(+) T-cell responses against viral infections.
Fri Jan 01 00:00:00 UTC 2016
Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.
The Journal of clinical investigation
Starobinets H,Ye J,Broz M,Barry K,Goldsmith J,Marsh T,Rostker F,Krummel M,Debnath J
11-7321 was used in Flow cytometry/Cell sorting to evaluate how autophagy inhibition impacts the antitumor immune response in immune-competent mouse models of melanoma and mammary cancer.
Thu Dec 01 00:00:00 UTC 2016
TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections.
The Journal of clinical investigation
Lewis GM,Wehrens EJ,Labarta-Bajo L,Streeck H,Zuniga EI
11-7321 was used in Flow cytometry/Cell sorting to uncover an eomesodermin-driven CD4 T cell program that is continuously suppressed by TGF-β signalling.
Mon Oct 03 00:00:00 UTC 2016
Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion.
The Journal of experimental medicine
Hu Y,Kim JH,He K,Wan Q,Kim J,Flach M,Kirchhausen T,Vortkamp A,Winau F
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Nov 14 00:00:00 UTC 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
11-7321 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 UTC 2016
Reprogramming the immunological microenvironment through radiation and targeting Axl.
Nature communications
Aguilera TA,Rafat M,Castellini L,Shehade H,Kariolis MS,Hui AB,Stehr H,von Eyben R,Jiang D,Ellies LG,Koong AC,Diehn M,Rankin EB,Graves EE,Giaccia AJ
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Dec 23 00:00:00 UTC 2016
Dendritic cell function and pathogen-specific T cell immunity are inhibited in mice administered levonorgestrel prior to intranasal Chlamydia trachomatis infection.
Scientific reports
Quispe Calla NE,Vicetti Miguel RD,Mei A,Fan S,Gilmore JR,Cherpes TL
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that levonorgestrel suppresses dendritic cell activation and function, and inhibits formation of pathogen-specific T-cell immunity.
Mon Nov 28 00:00:00 UTC 2016
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.
Cell
Parnas O,Jovanovic M,Eisenhaure TM,Herbst RH,Dixit A,Ye CJ,Przybylski D,Platt RJ,Tirosh I,Sanjana NE,Shalem O,Satija R,Raychowdhury R,Mertins P,Carr SA,Zhang F,Hacohen N,Regev A
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Thu Jul 30 00:00:00 UTC 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Jul 10 00:00:00 UTC 2015
Early virus-host interactions dictate the course of a persistent infection.
PLoS pathogens
Sullivan BM,Teijaro JR,de la Torre JC,Oldstone MB
11-7321 was used in Flow cytometry/Cell sorting to investigate the very early host-virus interactions that determine the establishment of viral persistence.
Thu Jan 01 00:00:00 UTC 2015
Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge.
Journal of immunology (Baltimore, Md. : 1950)
Cabrera-Perez J,Condotta SA,James BR,Kashem SW,Brincks EL,Rai D,Kucaba TA,Badovinac VP,Griffith TS
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that the recovery of CD4 T cells from sepsis-induced lymphopenia is accompanied by alterations to the composition and function of the Ag-specific CD4 T cell repertoire.
Sun Feb 15 00:00:00 UTC 2015
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Fri Mar 11 00:00:00 UTC 2016
Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses.
Molecular therapy : the journal of the American Society of Gene Therapy
Ip PP,Boerma A,Regts J,Meijerhof T,Wilschut J,Nijman HW,Daemen T
11-7321 was used in Flow cytometry/Cell sorting to study an rSFV-based vector which induces robust T-cell activity and has a potential for the treatment of HCV infections.
Tue Apr 01 00:00:00 UTC 2014
GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice.
Journal of immunology (Baltimore, Md. : 1950)
Shiomi A,Usui T,Ishikawa Y,Shimizu M,Murakami K,Mimori T
11-7321 was used in Flow cytometry/Cell sorting to investigate the importance of GM-CSF in the development of severe interstitial lung disease.
Tue Jul 15 00:00:00 UTC 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Flow Cytometry
Mon Jan 05 00:00:00 UTC 2015
Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function.
PloS one
Markwart R,Condotta SA,Requardt RP,Borken F,Schubert K,Weigel C,Bauer M,Griffith TS,Förster M,Brunkhorst FM,Badovinac VP,Rubio I
11-7321 was used in Flow cytometry/Cell sorting to investigate the nature of defects of T-cell immunity in post-acute phases of systemic inflammatory response, showing an induced loss of naive T-cells but no enduring cell-autonomous defects in T-cell function.
Thu Aug 27 00:00:00 UTC 2015
Hematopoietic not systemic impairment of Roquin expression accounts for intestinal inflammation in Roquin-deficient mice.
Scientific reports
Montufar-Solis D,Vigneswaran N,Nakra N,Schaefer JS,Klein JR
11-7321 was used in Flow cytometry/Cell sorting to investigate the intestinal immunopathology caused by insufficient Roquin, showing that hematopoietic, not systematic, impairment of Roquin expression accounts for pathology.
Mon May 12 00:00:00 UTC 2014
Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment.
Journal for immunotherapy of cancer
Spranger S,Koblish HK,Horton B,Scherle PA,Newton R,Gajewski TF
11-7321 was used in Flow cytometry/Cell sorting to assess the effectiveness of different immunotherapy combination treatments against the murine B16.SIY melanoma model.
Thu May 15 00:00:00 UTC 2014
Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola.
Molecular therapy : the journal of the American Society of Gene Therapy
Shedlock DJ,Aviles J,Talbott KT,Wong G,Wu SJ,Villarreal DO,Myles DJ,Croyle MA,Yan J,Kobinger GP,Weiner DB
11-7321 was used in Flow cytometry/Cell sorting to investigate the efficacy of cytotoxic T cell induction by a novel polyvalent-filovirus DNA vaccine against Marburg and Ebola.
Mon Jul 01 00:00:00 UTC 2013
Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma.
PloS one
Townsend KN,Spowart JE,Huwait H,Eshragh S,West NR,Elrick MA,Kalloger SE,Anglesio M,Watson PH,Huntsman DG,Lum JJ
11-7321 was used in Flow cytometry/Cell sorting to determine whether tumour vasculature influences the functional capacity of tumour infiltrating lymphocytes, and correlate this with survival in ovarian cancer patients.
Tue Mar 03 00:00:00 UTC 2015
Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity.
Molecular therapy : the journal of the American Society of Gene Therapy
Reyes-Sandoval A,Rollier CS,Milicic A,Bauza K,Cottingham MG,Tang CK,Dicks MD,Wang D,Longley RJ,Wyllie DH,Hill AV
11-7321 was used in Immunocytochemistry to investigate whether the two vaccine components adenovirus and modified vaccinia virus Ankara can be co-injected to enhance protection against malaria.
Wed Aug 01 00:00:00 UTC 2012
ORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic.
Molecular therapy : the journal of the American Society of Gene Therapy
Rintoul JL,Lemay CG,Tai LH,Stanford MM,Falls TJ,de Souza CT,Bridle BW,Daneshmand M,Ohashi PS,Wan Y,Lichty BD,Mercer AA,Auer RC,Atkins HL,Bell JC
11-7321 was used in Flow cytometry/Cell sorting to investigate the use of Parapoxvirus ovis for the treatment of cancer.
Fri Jun 01 00:00:00 UTC 2012
Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection.
Journal of virology
Garidou L,Heydari S,Gossa S,McGavern DB
11-7321 was used in Flow cytometry/Cell sorting to assess transforming growth factor beta inhibition as a viable approach to control a persistent viral infection.
Sun Jul 01 00:00:00 UTC 2012
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Journal of immunology (Baltimore, Md. : 1950)
Gowda NM,Wu X,Gowda DC
11-7321 was used in an ELISA assay to investigate TLR9 and MyD88 regulation of pro/anti-inflammatory cytokines in mice infected with Plasmodium yoelii.
Tue May 15 00:00:00 UTC 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
11-7321 was used in Flow cytometry/Cell sorting to determine the usefulness of a CBA/J-ML29 mouse model as a tool for evaluating the efficacy of vaccine candidates against LASV.
Tue Feb 14 00:00:00 UTC 2012
Failure to recruit anti-inflammatory CD103+ dendritic cells and a diminished CD4+ Foxp3+ regulatory T cell pool in mice that display excessive lung inflammation and increased susceptibility to Mycobacterium tuberculosis.
Infection and immunity
Leepiyasakulchai C,Ignatowicz L,Pawlowski A,Källenius G,Sköld M
11-7321 was used in Immunocytochemistry to increase our understanding of mechanisms that may regulate the host immune response in M. tuberculosis-infected lungs.
Thu Mar 01 00:00:00 UTC 2012
Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis.
PloS one
Cornish GH,Tung SL,Marshall D,Ley S,Seddon BP
Published figure using TNF alpha monoclonal antibody (Product # 11-7321-82) in Immunofluorescence
Fri Jun 29 00:00:00 UTC 2012
The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.
Journal of immunology (Baltimore, Md. : 1950)
Brincks EL,Gurung P,Langlois RA,Hemann EA,Legge KL,Griffith TS
11-7321 was used in Flow cytometry/Cell sorting to study how TRAIL affects the T cell response and ultimately influences the outcome of viral infection.
Tue Nov 01 00:00:00 UTC 2011
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
11-7321 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 UTC 2011
Autoreactive Tbet-positive CD4 T cells develop independent of classic Th1 cytokine signaling during experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Yeh WI,McWilliams IL,Harrington LE
11-7321 was used in Flow cytometry/Cell sorting to study changes in expression of Tbet by CD4 T cells from distinct areas of the body following the onset of experimental autoimmune encephalomyelitis.
Tue Nov 15 00:00:00 UTC 2011
Preferential replication of vaccinia virus in the ovaries is independent of immune regulation through IL-10 and TGF-β.
Viral immunology
Zhao Y,Adams YF,Croft M
11-7321 was used in Flow cytometry/Cell sorting to study how the preferential replication of VACV in the ovaries may not be dependent on immune suppressive mechanisms in this tissue.
Sat Oct 01 00:00:00 UTC 2011
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Journal of immunology (Baltimore, Md. : 1950)
Ito H,Hoshi M,Ohtaki H,Taguchi A,Ando K,Ishikawa T,Osawa Y,Hara A,Moriwaki H,Saito K,Seishima M
11-7321 was used in Flow cytometry/Cell sorting to study the immunological effects of IDO in α-galactosylceramide (α-GalCer)-induced hepatitis.
Fri Oct 15 00:00:00 UTC 2010
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Journal of immunology (Baltimore, Md. : 1950)
Ito H,Hoshi M,Ohtaki H,Taguchi A,Ando K,Ishikawa T,Osawa Y,Hara A,Moriwaki H,Saito K,Seishima M
11-7321 was used in Flow cytometry/Cell sorting to study the immunological effects of IDO in α-galactosylceramide (α-GalCer)-induced hepatitis.
Fri Oct 15 00:00:00 UTC 2010
NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Zecher D,Li Q,Oberbarnscheidt MH,Demetris AJ,Shlomchik WD,Rothstein DM,Lakkis FG
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that NK cells downregulate homeostatic CD8+ T-cell proliferation in lymphopenic environments by competing for IL-15.
Tue Jun 15 00:00:00 UTC 2010
Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection.
Journal of virology
Garidou L,Heydari S,Truong P,Brooks DG,McGavern DB
11-7321 was used in Immunofluorescence to reveal that costimulatory pathways can be targeted to modulate the magnitude of an adoptive immunotherapeutic regimen.
Tue Sep 01 00:00:00 UTC 2009
Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.
Cell
Ueki Y,Lin CY,Senoo M,Ebihara T,Agata N,Onji M,Saheki Y,Kawai T,Mukherjee PM,Reichenberger E,Olsen BR
11-7321 was used in Flow cytometry/Cell sorting to demonstrate that Sh3bp2 "cherubism'' mice exhibit trabecular bone loss, TNF-α-dependent systemic inflammation, and cortical bone erosion.
Fri Jan 12 00:00:00 UTC 2007
The surprising kinetics of the T cell response to live antigenic cells.
Journal of immunology (Baltimore, Md. : 1950)
Tyznik AJ,Bevan MJ
11-7321 was used in Flow cytometry/Cell sorting to demonstrate dramatic differences in host T cell responses to noninflammatory Ags compared with responses to pathogens.
Mon Oct 15 00:00:00 UTC 2007
