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Invitrogen
TNFAIP8L2 Recombinant Rabbit Monoclonal Antibody (19H35L22)
FIGURE: 1 / 3
TNFAIP8L2 Antibody (703165) in ICC/IF
Knockdown of TNFAIP8L2 was achieved by transfecting RAW 264.7 cells with specific siRNA (Silencer® select Product # s35946, s35945). Immunofluorescence analysis was performed on RAW 264.7 cells (untransfected, panel a-d), transfected with TNFAIP8L2 specific siRNA (panel i-l) or non-specific scrambled siRNA (panels e-h). Cells were fixed, permeabilized, and labeled with Anti-TNFAIP8L2 Recombinant Rabbit Mono... View More
Product Details
703165
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
19H35L22
Immunogen
Protein corresponding to human TNFAIP8L2 [aa45-aa184]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2784566
Product Specific Information
This antibody is predicted to react with Human, Mouse, Monkey, Pig, Horse, Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
TNFAIP8L2 - Tumor necrosis factor alpha-induced protein 8-like protein 2 (also known as TIPE2) acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. It is a negative regulator of Toll-like receptor and T-cell receptor functions. TIPE2 prevents hyperresponsiveness of the immune system and maintains immune homeostasis. It inhibits JUN/AP1 and NF-kappa-B activation. TIPE2 also promotes Fas-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inflammation factor 20; Inflammation factor protein 20; TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; TP8L2; Tumor necrosis factor alpha-induced protein 8-like protein 2; tumor necrosis factor, alpha induced protein 8 like 2; tumor necrosis factor, alpha-induced protein 8-like 2; tumor necrosis factor, alpha-induced protein 8-like protein 2
Gene Aliases: 1810019A08Rik; AW610835; TIPE2; TNFAIP8L2
UniProt ID: (Human) Q6P589, (Mouse) Q9D8Y7
Entrez Gene ID: (Human) 79626, (Mouse) 69769
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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