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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MCF-7 whole cell, SW620 whole cell, COS7 whole cell, SKOV whole cell, JURKAT whole cell. IHC: Human Intestinal Cancer Tissue, Human Mammary Cancer Tissue.
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: TNF alpha-induced protein 8-like protein 3; TNFAIP8-like protein 3; Tumor necrosis factor alpha-induced protein 8-like protein 3; tumor necrosis factor, alpha induced protein 8 like 3; tumor necrosis factor, alpha-induced protein 8-like 3
Gene Aliases: TIPE3; TNFAIP8L3
UniProt ID: (Human) Q5GJ75
Entrez Gene ID: (Human) 388121
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