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Abnova
TNP1 Monoclonal Antibody (1B5)
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Product Details
H00007141-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
1B5
Immunogen
TNP1 (AAH29516.1, 1 a.a. approximately 55 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.46 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSTSRKLKSH GMRRSKSRSP HKGVKRGGSK RKYRKGNLKS RKRGDDANRN YRSHL
Target Information
TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines. Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 ). Sequence Note: removed 4 bases from the 5' end that did not align to the reference genome assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Spermatid nuclear transition protein 1; STP-1; tnp; TP-1; transition protein 1 (during histone to protamine replacement)
Gene Aliases: TNP1; TP1
UniProt ID: (Human) P09430
Entrez Gene ID: (Human) 7141
single strand break repair
nucleosome disassembly
chromatin remodeling
chromatin silencing
multicellular organism development
spermatid development
spermatid nucleus differentiation
spermatid nucleus elongation
sexual reproduction
sperm motility
fertilization, exchange of chromosomal proteins
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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