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TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: importin 2; importin beta 2; Importin beta-2; karyopherin (importin) beta 2; Karyopherin beta-2; M9 region interaction protein; MAPKAP1; MIP; MSIN1; SAPK 1; SIN-1; SIN1; SIN1g; Transportin-1
Gene Aliases: AU021749; BOS_19620; D13Ertd688e; IPO2; KPNB2; MIP; MIP1; TNPO1; TRN
UniProt ID: (Human) Q92973, (Bovine) Q3SYU7, (Mouse) Q8BFY9
Entrez Gene ID: (Dog) 478093, (Human) 3842, (Bovine) 767620, (Rat) 309126, (Mouse) 238799
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