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Invitrogen
TNPO1 Polyclonal Antibody
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FIGURE: 1 / 2
TNPO1 Antibody (PA5-116066) in ICC/IF
Immunocytochemistry analysis of TNPO1 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116066). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-116066
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TNPO1(Accession Q92973), corresponding to amino acid residues P853-V898.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900700
Product Specific Information
Antibody detects endogenous levels of total Transportin 1.
Target Information
TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: importin 2; importin beta 2; Importin beta-2; karyopherin (importin) beta 2; Karyopherin beta-2; M9 region interaction protein; MAPKAP1; MIP; MSIN1; SAPK 1; SIN-1; SIN1; SIN1g; Transportin-1
Gene Aliases: AU021749; D13Ertd688e; IPO2; KPNB2; MIP; MIP1; TNPO1; TRN
UniProt ID: (Human) Q92973, (Mouse) Q8BFY9
Entrez Gene ID: (Human) 3842, (Rat) 309126, (Mouse) 238799
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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