Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: A549, HeLa, Jurkat, NT2D1.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ32746; Target of Myb-like protein 2; target of myb1-like 2; TOM1-like protein 2; UNQ3124
Gene Aliases: TOM1L2
UniProt ID: (Human) Q6ZVM7
Entrez Gene ID: (Human) 146691
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