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TOMM40 Monoclonal Antibody (5E2C5)

TOMM40 Antibody in Immunocytochemistry (ICC/IF)

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TOMM40 Antibody (66658-1-IG) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using (Product # 66658-1-IG) (TOMM40 antibody) at dilution of 1:100 and CoraLite488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

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Product Details

66658-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:50,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5E2C5

Immunogen

TOMM40 Fusion Protein Ag13065 (1-361 aa encoded by BC017224)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGNVLAASS PPAGPPPPPA PALVGLPPPP PSPPGFTLPP LGGSLGAGTS TSRSSERTPG AATASASGAA EDGACGCLPN PGTFEECHRK CKELFPIQME GVKLTVNKGL SNHFQVNHTV ALSTIGESNY HFGVTYVGTK QLSPTEAFPV LVGDMDNSGS LNAQVIHQLG PGLRSKMAIQ TQQSKFVNWQ VDGEYRGSDF TAAVTLGNPD VLVGSGILVA HYLQSITPCL ALGGELVYHR RPGEEGTVMS LAGKYTLNNW LATVTLGQAG MHATYYHKAS DQLQVGVEFE ASTRMQDTSV SFGYQLDLPK ANLLFKGSVD SNWIVGATLE KKLPPLPLTL ALGAFLNHRK NKFQCGFGLT IG (1-361 aa encoded by BC017224)

Target Information

TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane complex that is essential for protein import into mitochondria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Structural insight into the SAM-mediated assembly of the mitochondrial TOM core complex.

Science (New York, N.Y.)

Wang Q,Guan Z,Qi L,Zhuang J,Wang C,Hong S,Yan L,Wu Y,Cao X,Cao J,Yan J,Zou T,Liu Z,Zhang D,Yan C,Yin P

Fri Sep 17 00:00:00 UTC 2021

A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.

Science signaling

Ernst O,Sun J,Lin B,Banoth B,Dorrington MG,Liang J,Schwarz B,Stromberg KA,Katz S,Vayttaden SJ,Bradfield CJ,Slepushkina N,Rice CM,Buehler E,Khillan JS,McVicar DW,Bosio CM,Bryant CE,Sutterwala FS,Martin SE,Lal-Nag M,Fraser IDC

Tue Aug 03 00:00:00 UTC 2021

Dynamic Regulation of Mitochondrial Import by the Ubiquitin System.

Molecular cell

Phu L,Rose CM,Tea JS,Wall CE,Verschueren E,Cheung TK,Kirkpatrick DS,Bingol B

Thu Mar 05 00:00:00 UTC 2020

Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy.

Apoptosis : an international journal on programmed cell death

Zhu Y,Han XQ,Sun XJ,Yang R,Ma WQ,Liu NF

Mon Jun 01 00:00:00 UTC 2020

'Governor vessel-unblocking and mind-regulating' acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion.

International journal of molecular medicine

Su X,Wu Z,Mai F,Fan Z,Du S,Qian H,Zhu J

Tue Jan 01 00:00:00 UTC 2019

'Governor vessel-unblocking and mind-regulating' acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion.

International journal of molecular medicine

Su X,Wu Z,Mai F,Fan Z,Du S,Qian H,Zhu J

Tue Jan 01 00:00:00 UTC 2019

'Governor vessel-unblocking and mind-regulating' acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion.

International journal of molecular medicine

Su X,Wu Z,Mai F,Fan Z,Du S,Qian H,Zhu J

Tue Jan 01 00:00:00 UTC 2019

'Governor vessel-unblocking and mind-regulating' acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion.

International journal of molecular medicine

Su X,Wu Z,Mai F,Fan Z,Du S,Qian H,Zhu J

Tue Jan 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: haymaker protein; Mitochondrial import receptor subunit TOM40 homolog; mitochondrial outer membrane protein; mitochondrial outer membrane protein 35; Mitochondrial outer membrane protein of 35 kDa; Mitochondrial outer membrane protein of 38 kDa; MOM35; OM38; outer membrane protein 38 kDa; p38.5; PER EC1; Protein Haymaker; Translocase of outer membrane 40 kDa subunit homolog; translocase of outer mitochondrial membrane 40 homolog

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Gene Aliases: AW539759; C19orf1; D19S1177E; Mom35; OM38; PER-EC1; PEREC1; TOM40; Tom40a; TOMM40

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UniProt ID: (Human) O96008, (Rat) Q75Q40, (Mouse) Q9QYA2

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Entrez Gene ID: (Human) 10452, (Rat) 308416, (Mouse) 53333

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Function(s)

protein transmembrane transporter activity protein channel activity porin activity

Process(es)

protein targeting to mitochondrion ion transport macroautophagy protein import into mitochondrial matrix protein transport transmembrane transport protein transmembrane transport transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TOMM40 Monoclonal Antibody (5E2C5)

TOMM40 Antibody (66658-1-IG) in ICC/IF

Product Details

66658-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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