Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
23758-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TPCN1 Fusion Protein Ag20607 (1-112 aa encoded by BC136795)
Conjugate
Form
Liquid
Concentration
0.46 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAVSLDDDV PLILTLDEGG SAPLAPSNGL GQEELPSKNG GSYAIHDSQA PSLSSGGESS PSSPAHNWEM NYQEAAIYLQ EGENNDKFFT HPKDAKALAA YLFAHNHLFY LME (1-112 aa encoded by BC136795)
Target Information
TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ20612; Two pore calcium channel protein 1; Two pore channel protein 1; two-pore channel 1; two-pore channel 1, homolog; two-pore segment channel 1; Voltage-dependent calcium channel protein TPC1
Gene Aliases: 5730403B01Rik; KIAA1169; mKIAA1169; TPC1; TPCN1
UniProt ID: (Human) Q9ULQ1, (Mouse) Q9EQJ0
Entrez Gene ID: (Human) 53373, (Mouse) 252972
transport
ion transport
calcium ion transport
ion transmembrane transport
regulation of ion transmembrane transport
transmembrane transport
calcium ion transmembrane transport
membrane depolarization during action potential
positive regulation of autophagy
release of sequestered calcium ion into cytosol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support