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Invitrogen
TPCN1 Polyclonal Antibody
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TPCN1 Antibody (PA5-90758) in WB
Western blot analysis of TPCN1 in extracts of Rat lung. Samples were incubated with TPCN1 Polyclonal antibody (Product # PA5-90758) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-90758
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 692-816 of human TPCN1 (NP_0603712)
Conjugate
Form
Liquid
Concentration
2.37 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806224
Product Specific Information
Immunogen sequence: FRMNYSRKNQ DSEVDGGITL EKEISKEELV AVLELYREAR GASSDVTRLL ETLSQMERYQ QHSMVFLGRR SRTKSDLSLK MYQEEIQEWY EEHAREQEQQ RQLSSSAAPA AQQPPGSRQR SQTVT; Positive Samples: Rat lung; Cellular Location: Endosome membrane, Lysosome membrane, Multi-pass membrane protein
Target Information
TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20612; Two pore calcium channel protein 1; two pore channel 1; Voltage-dependent calcium channel protein TPC1; voltage-gated Ca channel
Gene Aliases: 5730403B01Rik; Kiaa1169; mKIAA1169; Tpc1; Tpcn1
UniProt ID: (Mouse) Q9EQJ0, (Rat) Q9WTN5
Entrez Gene ID: (Mouse) 252972, (Rat) 246215
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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