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Product Details
TPC1-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within TMD7 and TMD8 on human TPC1 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20612; Two pore calcium channel protein 1; two pore channel 1; Two pore channel protein 1; two-pore channel 1; two-pore channel 1, homolog; two-pore segment channel 1; Voltage-dependent calcium channel protein TPC1; voltage-gated Ca channel
Gene Aliases: 5730403B01Rik; KIAA1169; mKIAA1169; TPC1; TPCN1
UniProt ID: (Human) Q9ULQ1, (Mouse) Q9EQJ0, (Rat) Q9WTN5
Entrez Gene ID: (Human) 53373, (Mouse) 252972, (Rat) 246215
transport
ion transport
calcium ion transport
ion transmembrane transport
regulation of ion transmembrane transport
transmembrane transport
calcium ion transmembrane transport
membrane depolarization during action potential
positive regulation of autophagy
release of sequestered calcium ion into cytosol
biological_process
Performance Guarantee
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