Proteintech

TPD52L2 Polyclonal Antibody

TPD52L2 Antibody in Immunocytochemistry (ICC/IF)

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TPD52L2 Antibody (11795-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using (Product # 11795-1-AP) (TPD52L2 antibody), at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

TPD52L2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

TPD52L2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11795-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TPD52L2 Fusion Protein Ag2364 (1-201 aa encoded by BC006804)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MDSAGQDIN LNSPNKGLLS DSMTDVPVDT GVAARTPAVE GLTEAEEEEL RAELTKVEEE IVTLRQVLAA KERHCGELKR RLGLSTLGEL KQNLSRSWHD VQVSSAYVKT SEKLGEWNEK VTQSDLYKKT QETLSQAGQK TSAALSTVGS AISRKLGDMR NSATFKSFED RVGTIKSKVV GDRENGSDNL PSSAGSGDKP LS (1-201 aa encoded by BC006804)

Target Information

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Tumor protein D54 binds intracellular nanovesicles via an extended amphipathic region.

The Journal of biological chemistry

Reynaud A,Magdeleine M,Patel A,Gay AS,Debayle D,Abelanet S,Antonny B

Fri Jul 01 00:00:00 UTC 2022

Investigation of Transcript Variant 6 of TPD52L2 as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer.

Oxidative medicine and cellular longevity

Zhang X,O'Brien D,Zhang X

Fri Sep 09 00:00:00 UTC 2022

Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.

Cell & bioscience

Abe Y,Mukudai Y,Kurihara M,Houri A,Chikuda J,Yaso A,Kato K,Shimane T,Shirota T

Sat Jul 03 00:00:00 UTC 2021

Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway.

Neoplasma

Wang Z,Li Y,Fan L,Zhao Q,Tan B,Liu R,Li F

Sun Mar 01 00:00:00 UTC 2020

TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling.

Carcinogenesis

Qiang Z,Jun-Jie L,Hai W,Hong L,Bing-Xi L,Lei C,Wei X,Ya-Wei L,Huang A,Song-Tao Q,Yun-Tao L

Fri Feb 09 00:00:00 UTC 2018

TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling.

Carcinogenesis

Qiang Z,Jun-Jie L,Hai W,Hong L,Bing-Xi L,Lei C,Wei X,Ya-Wei L,Huang A,Song-Tao Q,Yun-Tao L

Fri Feb 09 00:00:00 UTC 2018

Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.

BioMed research international

Ito C,Mukudai Y,Itose M,Kato K,Motohashi H,Shimane T,Kondo S,Shirota T

Tue Apr 24 00:00:00 UTC 2018

Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.

BioMed research international

Ito C,Mukudai Y,Itose M,Kato K,Motohashi H,Shimane T,Kondo S,Shirota T

Tue Apr 24 00:00:00 UTC 2018

Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.

BioMed research international

Ito C,Mukudai Y,Itose M,Kato K,Motohashi H,Shimane T,Kondo S,Shirota T

Tue Apr 24 00:00:00 UTC 2018

Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.

BioMed research international

Ito C,Mukudai Y,Itose M,Kato K,Motohashi H,Shimane T,Kondo S,Shirota T

Tue Apr 24 00:00:00 UTC 2018

Increased expression of tumor protein D54 is associated with clinical progression and poor prognosis in patients with prostate cancer.

Oncology letters

Ren L,Chen J,Zhang X

Fri Dec 01 00:00:00 UTC 2017

Increased expression of tumor protein D54 is associated with clinical progression and poor prognosis in patients with prostate cancer.

Oncology letters

Ren L,Chen J,Zhang X

Fri Dec 01 00:00:00 UTC 2017

Opposite effects of tumor protein D (TPD) 52 and TPD54 on oral squamous cell carcinoma cells.