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Immunogen sequence: ATFKSFEDRV GTIKSKVVGD RENGSDNLPS SAGSGDKPLS DPAPF
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686A1765; HCCR-binding protein 2; hD54; Tumor protein D52-like 2; Tumor protein D54
Gene Aliases: 2810411G23Rik; AU016537; C86069; D54; TPD52L2; TPD54
UniProt ID: (Human) O43399, (Rat) Q6PCT3, (Mouse) Q9CYZ2
Entrez Gene ID: (Human) 7165, (Rat) 296480, (Mouse) 66314
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