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Product Details
PA5-22012
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human Tropomyosin 2 Recombinant protein.
Conjugate
Form
Liquid
Concentration
0.66 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11156208
Product Specific Information
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (84%), Pig (98%), Rabbit (99%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TPM2 (tropomyosin 2) is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers. TPM2 binds to actin filaments in muscle and non-muscle cells. Plays a central role in association with the troponin complex in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis dital 1A/2B, and cap myopathy 2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-tropomyosin; epididymis secretory protein Li 273; nemaline myopathy type 4; RP11-112J3.4; tropomyosin; Tropomyosin beta chain; Tropomyosin-2
Gene Aliases: AMCD1; DA1; DA2B; HEL-S-273; NEM4; TMSB; TPM2
UniProt ID: (Human) P07951
Entrez Gene ID: (Human) 7169
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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