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FIGURE: 1 / 1
TRAM2 Antibody (PA5-95107) in WB
Western blot analysis of TRAM2 in Lane 1: recombinant mouse TRAM2 protein (10 ng), Lane 2: recombinant mouse TRAM2 protein (5 ng), Lane 3: recombinant mouse TRAM2 protein (2.5 ng). Samples were incubated with TRAM2 polyclonal antibody (Product # PA5-95107).
Product Details
PA5-95107
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse TRAM2 (309-325aa RFIHSQLRHWREYWKEQ).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806913
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TRAM-like protein; Translocating chain-associated membrane protein 2; translocating chain-associating membrane protein 2
Gene Aliases: C330003D03Rik; KIAA0057; TRAM2
UniProt ID: (Human) Q15035, (Mouse) Q924Z5
Entrez Gene ID: (Rat) 100361830, (Human) 9697, (Mouse) 170829
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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