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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 -dependent manner.
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Protein Aliases: MGC119173; OTTHUMP00000017858; TLT-1; TREM; Trem-like transcript 1 protein; Triggering receptor expressed on myeloid cells; triggering receptor expressed on myeloid cells-like 1; triggering receptor expressed on myeloid cells-like 1c; triggering receptor expressed on myeloid cells-like 1d; triggering receptor expressed on myeloid cells-like 1e; Triggering receptor expressed on myeloid cells-like protein 1
Gene Aliases: 5430401J17Rik; dJ238O23.3; GLTL1825; PRO3438; RGD1565175; TLT-1; TLT1; TREML1; UNQ1825/PRO3438
UniProt ID: (Human) Q86YW5, (Mouse) Q8K558
Entrez Gene ID: (Human) 340205, (Mouse) 71326, (Rat) 501096
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