Proteintech

TRIM11 Polyclonal Antibody

TRIM11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TRIM11 Antibody (10851-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using (Product # 10851-1-AP) (TRIM11 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Product Details

10851-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 5 publications 5 publications

Immunoprecipitation (IP)

View 5 publications 5 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TRIM11 Fusion Protein Ag1308 (1-202 aa encoded by BC011629)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MELRTVCRV PGLVETLRRF RGDVTLDPDT ANPELILSED RRSVQRGDLR QALPDSPERF DPGPCVLGQE RFTSGRHYWE VEVGDRTSWA LGVCRENVNR KEKGELSAGN GFWILVFLGS YYNSSERALA PLRDPPRRVG IFLDYEAGHL SFYSATDGSL LFIFPEIPFS GTLRPLFSPL SSSPTPMTIC RPKGGSGDTL APQ (1-202 aa encoded by BC011629)

Target Information

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.

Bioengineered

Jin X,Shao X,Pang W,Wang Z,Huang J

Sun May 01 00:00:00 UTC 2022

Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.

Cell biology international

He F,Wu Z,Wang Y,Yin L,Lu S,Dai L

Sat Jan 01 00:00:00 UTC 2022

Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.

Cell biology international

He F,Wu Z,Wang Y,Yin L,Lu S,Dai L

Sat Jan 01 00:00:00 UTC 2022

The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM_2.5 exposure-induced pulmonary fibrosis of mice.

Journal of hazardous materials

Zhang Y,Liu Q,Ning J,Jiang T,Kang A,Li L,Pang Y,Zhang B,Huang X,Wang Q,Bao L,Niu Y,Zhang R

Wed Jun 15 00:00:00 UTC 2022

The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM_2.5 exposure-induced pulmonary fibrosis of mice.

Journal of hazardous materials

Zhang Y,Liu Q,Ning J,Jiang T,Kang A,Li L,Pang Y,Zhang B,Huang X,Wang Q,Bao L,Niu Y,Zhang R

Wed Jun 15 00:00:00 UTC 2022

The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM_2.5 exposure-induced pulmonary fibrosis of mice.

Journal of hazardous materials

Zhang Y,Liu Q,Ning J,Jiang T,Kang A,Li L,Pang Y,Zhang B,Huang X,Wang Q,Bao L,Niu Y,Zhang R

Wed Jun 15 00:00:00 UTC 2022

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

International journal of biological sciences

Tang J,Tian Z,Liao X,Wu G

Fri Jan 14 00:00:00 UTC 2022

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

International journal of biological sciences

Tang J,Tian Z,Liao X,Wu G

Fri Jan 14 00:00:00 UTC 2022

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

International journal of biological sciences

Tang J,Tian Z,Liao X,Wu G

Fri Jan 14 00:00:00 UTC 2022

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Neoplasia (New York, N.Y.)

Tang J,Luo Y,Tian Z,Liao X,Cui Q,Yang Q,Wu G

Tue Sep 01 00:00:00 UTC 2020

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Neoplasia (New York, N.Y.)

Tang J,Luo Y,Tian Z,Liao X,Cui Q,Yang Q,Wu G

Tue Sep 01 00:00:00 UTC 2020

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Neoplasia (New York, N.Y.)

Tang J,Luo Y,Tian Z,Liao X,Cui Q,Yang Q,Wu G

Tue Sep 01 00:00:00 UTC 2020

miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.

Pathology, research and practice

Song Z,Guo Q,Wang H,Gao L,Wang S,Liu D,Liu J,Qi Y,Lin B

Sun Nov 01 00:00:00 UTC 2020

Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.

BioMed research international

Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

Thu Jul 02 00:00:00 UTC 2020

Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.

BioMed research international

Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

Thu Jul 02 00:00:00 UTC 2020

Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.

BioMed research international

Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

Thu Jul 02 00:00:00 UTC 2020

The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen W,Peng R,Sun Y,Liu H,Zhang L,Peng H,Zhang Z

Tue Oct 01 00:00:00 UTC 2019

The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen W,Peng R,Sun Y,Liu H,Zhang L,Peng H,Zhang Z

Tue Oct 01 00:00:00 UTC 2019

Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals.

Human genome variation

Stittrich AB,Ashworth J,Shi M,Robinson M,Mauldin D,Brunkow ME,Biswas S,Kim JM,Kwon KS,Jung JU,Galas D,Serikawa K,Duerr RH,Guthery SL,Peschon J,Hood L,Roach JC,Glusman G

Fri Apr 15 00:00:00 UTC 2016

Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals.

Human genome variation

Stittrich AB,Ashworth J,Shi M,Robinson M,Mauldin D,Brunkow ME,Biswas S,Kim JM,Kwon KS,Jung JU,Galas D,Serikawa K,Duerr RH,Guthery SL,Peschon J,Hood L,Roach JC,Glusman G

Fri Apr 15 00:00:00 UTC 2016

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Oncogene

Di K,Linskey ME,Bota DA

Thu Oct 17 00:00:00 UTC 2013

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Oncogene

Di K,Linskey ME,Bota DA

Thu Oct 17 00:00:00 UTC 2013

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Oncogene

Di K,Linskey ME,Bota DA

Thu Oct 17 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: E3 ubiquitin-protein ligase TRIM11; Protein BIA1; RING finger protein 92; tripartite motif-containing 11; Tripartite motif-containing protein 11

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Gene Aliases: BIA1; RNF92; TRIM11

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UniProt ID: (Human) Q96F44

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Entrez Gene ID: (Human) 81559

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Function(s)

protein binding transcription factor binding zinc ion binding ligase activity protein domain specific binding ubiquitin protein ligase activity

Process(es)

protein ubiquitination negative regulation of viral transcription innate immune response negative regulation of transcription, DNA-templated negative regulation of viral entry into host cell positive regulation of viral entry into host cell negative regulation of neurogenesis defense response to virus negative regulation of viral release from host cell

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TRIM11 Polyclonal Antibody

TRIM11 Antibody (10851-1-AP) in IHC (P)

Product Details

10851-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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