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Invitrogen
TRIM15 Polyclonal Antibody
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Product Details
PA5-100357
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TRIM15(Accession Q9C019), corresponding to amino acid residues M378-L428.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849870
Product Specific Information
Antibody detects endogenous levels of total TRIM15.
Target Information
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM15; RING finger protein 93; tripartite motif protein 15; tripartite motif-containing 15; tripartite motif-containing protein 15; Zinc finger protein 178; Zinc finger protein B7
Gene Aliases: 1810012B10Rik; RNF93; TRIM15; ZNF178; ZNFB7
UniProt ID: (Human) Q9C019
Entrez Gene ID: (Human) 89870, (Mouse) 69097
positive regulation of type I interferon production
innate immune response
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of RIG-I signaling pathway
negative regulation of intracellular transport of viral material
negative regulation of viral release from host cell
mesodermal cell fate determination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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