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TRIM37 Antibody (PA5-30094) in WB
Western Blot using TRIM37 Polyclonal Antibody (Product # PA5-30094). Sample (30 µg of whole cell lysate). Lane A: Jurkat. Lane B: Raji. Lane C: K562. Lane D: NCI-H929. 7.5% SDS PAGE. TRIM37 Polyclonal Antibody (Product # PA5-30094) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-30094
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human TRIM37. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547568
Product Specific Information
Recommended positive controls: Jurkat, Raji, K562, NCI-H929, Rat2.
Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Chicken (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; tripartite motif protein 37; Tripartite motif-containing protein 37
Gene Aliases: KIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972
Entrez Gene ID: (Human) 4591, (Rat) 360592
negative regulation of transcription from RNA polymerase II promoter
biological_process
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
transcription, DNA-templated
Performance Guarantee
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