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Invitrogen
TRIM37 Monoclonal Antibody (2D11)
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Product Details
MA5-19380
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2D11
Immunogen
TRIM37 (NP_056109, 865 a.a. ~ 964 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609952
Product Specific Information
Peptide Sequence: GHLEGLQMTD LENNSETGEL QPVLPEGASA APEEGMSSDS DIECDTENEE QEEHTSVGGF HDSFMVMTQP PDEDTHSSFP DGEQIGPEDL SFNTDENSGR
Target Information
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; Tripartite motif-containing protein 37
Gene Aliases: KIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972
Entrez Gene ID: (Human) 4591
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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