Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase TRIM58; Protein BIA2; RING-type E3 ubiquitin transferase TRIM58; tripartite motif-containing 58; Tripartite motif-containing protein 58
Gene Aliases: BIA2; TRIM58
UniProt ID: (Human) Q8NG06
Entrez Gene ID: (Human) 25893
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