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Product Details
H00055223-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIM62 (AAH01222.1, 1 a.a. approximately 475 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP ALAPSLKLAN IVERYSSFPL DAILNARRAA RPCQAHDKVK LFCLTDRALL CFFCDEPALH EQHQVTGIDD AFDELQRELK DQLQALQDSE REHTEALQLL KRQLAETKSS TKSLRTTIGE AFERLHRLLR ERQKAMLEEL EADTARTLTD IEQKVQRYSQ QLRKVQEGAQ ILQERLAETD RHTFLAGVAS LSERLKGKIH ETNLTYEDFP TSKYTGPLQY TIWKSLFQDI HPVPAALTLD PGTAHQRLIL SDDCTIVAYG NLHPQPLQDS PKRFDVEVSV LGSEAFSSGV HYWEVVVAEK TQWVIGLAHE AASRKGSIQI QPSRGFYCIV MHDGNQYSAC TEPWTRLNVR DKLDKVGVFL DYDQGLLIFY NADDMSWLYT FREKFPGKLC SYFSPGQSHA NGKNVQPLRI NTVRI
Target Information
E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ductal epithelium-associated RING Chromosome 1; E3 ubiquitin-protein ligase TRIM62; tripartite motif-containing 62; Tripartite motif-containing protein 62
Gene Aliases: DEAR1; TRIM62
UniProt ID: (Human) Q9BVG3
Entrez Gene ID: (Human) 55223
negative regulation of epithelial to mesenchymal transition
protein ubiquitination
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
interferon-gamma-mediated signaling pathway
regulation of viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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