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TRIM62 Antibody (PA5-116643) in IHC (P)
Immunohistochemistry analysis of TRIM62 in paraffin-embedded human colon. Samples were incubated with TRIM62 Polyclonal antibody (Product # PA5-116643) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116643
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_0606772)
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901274
Product Specific Information
Positive Samples: A-431, Mouse brain
Immunogen sequence: HEQHQVTGID DAFDELQREL KDQLQALQDS EREHTEALQL LKRQLAETKS STKSLRTTIG EAFERLHRLL RERQKAMLEE LEADTARTLT DIEQKVQRYS QQLRKVQEGA QILQERLAET DRHTFLAGVA SLSERLKGKI HETNLTYEDF PTSKYTGPLQ Y
Target Information
E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ductal epithelium-associated RING Chromosome 1; E3 ubiquitin-protein ligase TRIM62; tripartite motif-containing 62; Tripartite motif-containing protein 62
Gene Aliases: 6330414G21Rik; AI450348; DEAR1; TRIM62
UniProt ID: (Human) Q9BVG3, (Mouse) Q80V85
Entrez Gene ID: (Human) 55223, (Rat) 313045, (Mouse) 67525
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of epithelial to mesenchymal transition
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
regulation of viral release from host cell
protein ubiquitination
interferon-gamma-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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