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Product Details
24369-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIM67 Fusion Protein Ag21632 (26-102 aa encoded by BC157055)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VCLPCARTI AVQTPDGEQH LPQPLLLSRG SGLQAGAAAA ASLEHDAAAG PACGGAGGSA AGGLGGGAGG GGDHADKL (26-102 aa encoded by BC157055 )
Target Information
The TRIM67 gene encodes a member of the tripartite motif (TRIM) protein family, which is involved in various cellular processes including protein ubiquitination, signal transduction, and immune responses. TRIM67 contains RING, B-box, and coiled-coil domains, characteristic of TRIM proteins, which facilitate interactions with other proteins and contribute to its role in ubiquitination and cellular regulation. TRIM67 is notably expressed in the brain and has been associated with neurodevelopmental processes, particularly influencing neuronal differentiation and synapse formation. This gene plays a regulatory role in signaling pathways that are critical for neural development, and mutations or dysregulation in TRIM67 have been linked to neurodevelopmental disorders and cognitive deficits. Additionally, TRIM67's involvement in protein degradation and signal modulation may impact cellular architecture and brain function. Ongoing research seeks to elucidate TRIM67's precise mechanisms and potential therapeutic targets for neurological conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: TRIM9-like protein; TRIM9-like protein TNL; Tripartite motif-containing protein 67
Gene Aliases: D130049O21Rik; TNL; TRIM67
UniProt ID: (Human) Q6ZTA4, (Mouse) Q505D9
Entrez Gene ID: (Human) 440730, (Mouse) 330863
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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