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Osenses
TRPC3 Polyclonal Antibody
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Product Details
OSR00065W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse TRPC3 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPC3.
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hTrp3; ion channel protein; mTrp3; Receptor-activated cation channel TRP3; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; Transient receptor protein 3; TRP-3; Trp-related protein 3; TrpC3
Gene Aliases: Mwk; Trcp3; Trp3; Trpc3; TrpC3c; Trrp3
UniProt ID: (Mouse) Q9QZC1
Entrez Gene ID: (Rat) 60395, (Mouse) 22065
positive regulation of calcium ion transport into cytosol
response to ATP
response to calcium ion
calcium ion transmembrane transport
positive regulation of cardiac muscle hypertrophy in response to stress
transport
ion transport
calcium ion transport
manganese ion transport
regulation of cytosolic calcium ion concentration
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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