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Alomone Labs, LTD
TRPC7 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 2
TRPC7 (extracellular) Antibody (ACC-066-200UL) in ICC/IF
Expression of TRPC7 in rat PC12 cells - Cell surface detection of TRPC7 in intact living rat pheochromocytoma (PC12) cells using . A. Extracellular staining of cells using Anti-TRPC7 (extracellular) Antibody (#ACC-066), (1:50) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Live view of the cells.
Product Details
ACC-066-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)DQHVQDDTLHNVS, corresponding to amino acid residues 504-516 of human TRPC7, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
TRPC7 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC7 is probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC7 is also activated by diacylglycerol (DAG). Further, TRPC7 may also be activated by intracellular calcium store depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: capacitative calcium channel TRPC7; hTRP7; likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7; mTRP7; putative capacitative calcium channel; Short transient receptor potential channel 7; transient receptor potential cation channel, subfamily C, member 7; Transient receptor protein 7; TRP-7; TRP7 protein; TrpC7
Gene Aliases: TRP7; TRPC7; Trrp8
UniProt ID: (Human) Q9HCX4, (Mouse) Q9WVC5
Entrez Gene ID: (Human) 57113, (Rat) 282822, (Mouse) 26946
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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