Osenses

TRPL Polyclonal Antibody

Product Details

OST00137W-100UL

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

Immunohistochemistry (IHC)

1:300-1:2,000

Miscellaneous PubMed (MISC)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Fruit fly

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to an immunogenic carrier protein was used as the immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: TRPL.

Target Information

TRPL is a light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. This protein is required for vision in the dark and in dim light. TRPL binds calmodulin. Trp and trpl act together in the light response, although it is unclear whether as heteromultimers or distinct units. Also, TRPL forms a functional cation channel with trp-gamma. TRPL is activated by fatty acids, metabolic stress, inositols and GTP-binding proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The genome sequence of Drosophila melanogaster.

Science (New York, N.Y.)

Adams MD,Celniker SE,Holt RA,Evans CA,Gocayne JD,Amanatides PG,Scherer SE,Li PW,Hoskins RA,Galle RF,George RA,Lewis SE,Richards S,Ashburner M,Henderson SN,Sutton GG,Wortman JR,Yandell MD,Zhang Q,Chen LX,Brandon RC,Rogers YH,Blazej RG,Champe M,Pfeiffer BD,Wan KH,Doyle C,Baxter EG,Helt G,Nelson CR,Gabor GL,Abril JF,Agbayani A,An HJ,Andrews-Pfannkoch C,Baldwin D,Ballew RM,Basu A,Baxendale J,Bayraktaroglu L,Beasley EM,Beeson KY,Benos PV,Berman BP,Bhandari D,Bolshakov S,Borkova D,Botchan MR,Bouck J,Brokstein P,Brottier P,Burtis KC,Busam DA,Butler H,Cadieu E,Center A,Chandra I,Cherry JM,Cawley S,Dahlke C,Davenport LB,Davies P,de Pablos B,Delcher A,Deng Z,Mays AD,Dew I,Dietz SM,Dodson K,Doup LE,Downes M,Dugan-Rocha S,Dunkov BC,Dunn P,Durbin KJ,Evangelista CC,Ferraz C,Ferriera S,Fleischmann W,Fosler C,Gabrielian AE,Garg NS,Gelbart WM,Glasser K,Glodek A,Gong F,Gorrell JH,Gu Z,Guan P,Harris M,Harris NL,Harvey D,Heiman TJ,Hernandez JR,Houck J,Hostin D,Houston KA,Howland TJ,Wei MH,Ibegwam C,Jalali M,Kalush F,Karpen GH,Ke Z,Kennison JA,Ketchum KA,Kimmel BE,Kodira CD,Kraft C,Kravitz S,Kulp D,Lai Z,Lasko P,Lei Y,Levitsky AA,Li J,Li Z,Liang Y,Lin X,Liu X,Mattei B,McIntosh TC,McLeod MP,McPherson D,Merkulov G,Milshina NV,Mobarry C,Morris J,Moshrefi A,Mount SM,Moy M,Murphy B,Murphy L,Muzny DM,Nelson DL,Nelson DR,Nelson KA,Nixon K,Nusskern DR,Pacleb JM,Palazzolo M,Pittman GS,Pan S,Pollard J,Puri V,Reese MG,Reinert K,Remington K,Saunders RD,Scheeler F,Shen H,Shue BC,Sidén-Kiamos I,Simpson M,Skupski MP,Smith T,Spier E,Spradling AC,Stapleton M,Strong R,Sun E,Svirskas R,Tector C,Turner R,Venter E,Wang AH,Wang X,Wang ZY,Wassarman DA,Weinstock GM,Weissenbach J,Williams SM,Worley KC,Wu D,Yang S,Yao QA,Ye J,Yeh RF,Zaveri JS,Zhan M,Zhang G,Zhao Q,Zheng L,Zheng XH,Zhong FN,Zhong W,Zhou X,Zhu S,Zhu X,Smith HO,Gibbs RA,Myers EW,Rubin GM,Venter JC

Fri Mar 24 00:00:00 UTC 2000

The role of calmodulin-binding sites in the regulation of the Drosophila TRPL cation channel expressed in Xenopus laevis oocytes by ca2+, inositol 1,4,5-trisphosphate and GTP-binding proteins.

The Biochemical journal

Lan L,Brereton H,Barritt GJ

Sun Mar 15 00:00:00 UTC 1998

Coassembly of TRP and TRPL produces a distinct store-operated conductance.

Cell

Xu XZ,Li HS,Guggino WB,Montell C

Fri Jun 27 00:00:00 UTC 1997

Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene.

Neuron

Phillips AM,Bull A,Kelly LE

Wed Apr 01 00:00:00 UTC 1992

Bioinformatics

Protein Aliases: CG18345-PA; CG18345-PB; CG18345-PD; transient receptor Potential-Like; Transient-receptor-potential-like protein; TRP-like; trpl-PA; trpl-PB; trpl-PD

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Gene Aliases: CG1694; CG18345; Dmel\CG18345; Dmel_CG18345; DmTRPL; dTRPL; trp-l; TRP-Like; TRPL

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UniProt ID: (Fruit fly) P48994

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Entrez Gene ID: (Fruit fly) 36003

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Function(s)

cation channel activity calcium channel activity protein binding calmodulin binding light-activated ion channel activity store-operated calcium channel activity identical protein binding protein heterodimerization activity

Process(es)

cation transport calcium ion transport body fluid secretion phototransduction, visible light sensory perception of sound response to light stimulus calcium-mediated signaling calcium ion transmembrane transport cellular response to anoxia

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TRPL Polyclonal Antibody

Product Details

OST00137W-100UL

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (MISC)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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