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TRPM5 Antibody (ACC-045-200UL) in IHC (P)
Expression of TRPM5 in rat testes - Immunohistochemical staining of rat epididymis paraffin embedded sections using Anti-TRPM5 Antibody (#ACC-045), (1:100). TRPM5 is expressed in principal cells with in the epididymal epithelium (arrows). Hematoxilin is used as the counterstain.
Product Details
ACC-045-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GSGKKRGKFVKVPS(C), corresponding to amino acid residues 32-45 of mouse TRPM5, Intracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Caions. It is activated by lower concentrations of intracellular Ca, and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Long transient receptor potential channel 5; long transient receptor potential-related channel 5; LTrpC-5; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; Transient receptor potential cation channel subfamily M member 5; transient receptor potential cation channel, subfamily M, member 5; TRPM5
Gene Aliases: 9430099A16Rik; LTrpC-5; LTRPC5; MTR1; TRPM5
UniProt ID: (Human) Q9NZQ8, (Mouse) Q9JJH7
Entrez Gene ID: (Human) 29850, (Mouse) 56843, (Rat) 365391
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