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Product Details
10214-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSC22D1 Fusion Protein Ag0287 (2-144 aa encoded by BC000456)
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against an internal region of human TSC22D1.
Immunogen sequence: KSQWCRPVA MDLGVYQLRH FSISFLSSLL GTENASVRLD NSSSGASVVA IDNKIEQAMD LVKSHLMYAV REEVEVLKEQ IKELIEKNSQ LEQENNLLKT LASPEQLAQF QAQLQTGSPP ATTQPQGTTQ PPAQPASQGS GPTA (2-144 aa encoded by BC000456)
Target Information
TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cerebral protein 2; HUCEP-2; Regulatory protein TSC-22; regulatory protein Tsc22; RP11-269C23.2; TGFB-stimulated clone 22 homolog; TGFbeta-stimulated clone 22; transcriptional regulator TSC-22; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta stimulated clone 22; Transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22-related inducible leucine zipper 1b
Gene Aliases: AA589566; AW105905; Egr5; hucep-2; KIAA1994; Ptg-2; TGFB1I4; Tilz1b; TS22A; Tsc; TSC-22; TSC22; TSC22D1
UniProt ID: (Human) Q15714, (Mouse) P62500, (Rat) P62501
Entrez Gene ID: (Human) 8848, (Mouse) 21807, (Rat) 498545
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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